| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:Exo2 >=98% (HPLC)
CAS:304684-77-3
Purity:NULL Package:25mg;5mg Remarks:NULL
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| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:Exo2
CAS:304684-77-3
Purity:98% Package:100 mg；5 mg；50 mg
|
| Company Name: |
Focus Biomolecules
|
| Tel: |
855-362-8721 |
| Email: |
sales@focusbiomolecules.com |
| Products Intro: |
Product Name:Exo2
CAS:304684-77-3
Purity:98% by TLCNMR (Conforms) Package:$62.00/5mg;$248.00/25mg;
|
| Company Name: |
Riedel-de Haen AG
|
| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Product Name:Exo2
CAS:304684-77-3
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| | 2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol Basic information |
| Product Name: | 2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol | | Synonyms: | 2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol;Exo2;Exo2 >=98% (HPLC);Benzaldehyde, 4-hydroxy-3-methoxy-, 2-(5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)hydrazone | | CAS: | 304684-77-3 | | MF: | C18H18N4O2S | | MW: | 354.43 | | EINECS: | | | Product Categories: | | | Mol File: | 304684-77-3.mol | ![2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol Structure](CAS/20180703/GIF/304684-77-3.gif) |
| | 2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol Chemical Properties |
| Boiling point | 591.0±50.0 °C(Predicted) | | density | 1.44±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: >20mg/mL | | form | powder | | pka | 8.79±0.35(Predicted) | | color | yellow | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. |
| | 2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol Usage And Synthesis |
| Description | Exo2 (304684-77-3) disrupts the Golgi apparatus and stimulates Golgi-ER fusion in mammalian cells.1 May be used to completely ablate the Golgi apparatus.1 Like brefeldin A (BFA), it inhibits anterograde transport and disrupts morphology of the trans-Golgi network (TGN) but unlike BFA, it does not induce tubulation and merging of the TGN and endosomal compartments.2? It perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network, in contrast to cholera toxin.1,2 Accelerates degradation of perilipin-2 proteins.3 | | Definition | ChEBI: Exo2 is a member of phenols and a member of methoxybenzenes. | | References | 1) Feng et al. (2004), Retrograde transport of cholera toxin from the plasma membrane to the endoplasmic reticulum requires the trans-Golgi network but not the Golgi apparatus in Exo2-treated cells; EMBO Rep., 5 596
2) Spooner et al. (2008), The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network; Biochem. J., 414 471
3) Pauloin et al. (2016), The perilipin-2 (adipophilin) coat of cytosolic lipid droplets is regulated by an Arf1-dependent mechanism in the HC11 mouse mammary epithelial cells; Cell Biol. Int., 40 143 |
| | 2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol Preparation Products And Raw materials |
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