| Company Name: |
MedBioPharmaceutical Technology Inc
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| Tel: |
021-69568360 18916172912 |
| Email: |
order@med-bio.cn |
| Products Intro: |
Product Name:4-(4-Morpholinobutylthio)phenol
CAS:57055-82-0
Purity:98% Package:5mg; 25mg; 10mg; 1mg Remarks:Medbio
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| | 4-(4-Morpholinobutylthio)phenol Basic information |
| | 4-(4-Morpholinobutylthio)phenol Chemical Properties |
| storage temp. | -20°C | | solubility | DMSO: ≥80mg/mL | | form | powder | | color | white to tan | | Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
| | 4-(4-Morpholinobutylthio)phenol Usage And Synthesis |
| Description | MoTP (57055-82-0) specifically ablates zebrafish larval melanocytes. Melanocytotoxicity is dependent on tyrosinase activity.1,2 MoTP is a useful tool for elucidating melanocyte stem cell regeneration, recruitment and maintenance.3-5 | | References | 1) Yang et al. (2006), Small molecule-induced ablation and subsequent regeneration of larval zebrafish melanocytes; Development, 133 3563
2) Yang et al. (2007), Mutations in gfpt1 and skiv2I2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish; PLoS Genet., 3 e88
3) Hultman et al. (2009), Defects in ErbB-dependent establishment of adult melanocyte stem cells reveal independent origins for embryonic and regeneration melanocytes; PLoS Genet., 5 e1000544
4) Hultman et al. (2010), Differential contribution of direct-developing and stem cell-derived melanocytes to the zebrafish larval pigment pattern; Dev. Biol., 337 425
5) Hultman et al. (2008), Small molecule modifier screen for kit-dependent functions in zebrafish embryonic melanocytes; Zebrafish, 5 279 |
| | 4-(4-Morpholinobutylthio)phenol Preparation Products And Raw materials |
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