| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:STA-9584
CAS:906481-23-0
Package:25mg/RMB 12800;100mg/RMB 21500;50mg/RMB 16800
|
STA-9584 manufacturers
- STA-9584
-
- $1820.00 / 25mg
-
2024-10-24
- CAS:906481-23-0
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| | STA-9584 Basic information |
| | STA-9584 Chemical Properties |
| | STA-9584 Usage And Synthesis |
| Description | STA-9584 is a potent vascular disrupting agent, which exhibits potent antitumor activity by selectively targeting microvasculature at both the center and periphery of tumors. In vitro, 2-methoxy-5-(5-(3,4,5-trimethoxyphenyl)isoxazol-4-yl)aniline (STA-9122) (active metabolite of STA-9584 ) displayed increased potency relative to other tubulin-binding agents and was highly cytotoxic to tumor cells. STA-9584 induced significant tumor regressions in prostate and breast xenograft models in vivo and, in an aggressive syngeneic model, demonstrated superior tumor growth inhibition and a positive therapeutic index relative to combretastatin A-4 phosphate (CA4P). |
| | STA-9584 Preparation Products And Raw materials |
|