(R)-Praziquantel-d11
| 中文名称 | (R)-Praziquantel-d11 |
|---|---|
| 中文同义词 | (R)-吡喹酮-D11;(R)-吡喹酮-D11(吡喹酮杂质4);(R)-2-(环己烷-1-羰基-1,2,2,3,3,4,4,5,5,6,6-D11)-1,2,3,6,7,11B-六氢-4H-吡嗪并[2,1-A]异喹啉-4-酮 |
| 英文名称 | (R)-Praziquantel-d11 |
| 英文同义词 | (R)-Praziquantel-d11;(R)-2-(Cyclohexane-1-carbonyl-1,2,2,3,3,4,4,5,5,6,6-d11)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one;(11bR)-2-[(1,2,2,3,3,4,4,5,5,6,6-2H??)cyclohexane-1-carbonyl]-1H,2H,3H,4H,6H,7H,11bH-pyrazino[2,1-a]isoquinolin-4-one;Binimetinib Impurity;Binimetinib Impurity 8 |
| CAS号 | 1399880-38-6 |
| 分子式 | C19H24N2O2 |
| 分子量 | 312.41 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1399880-38-6.mol |
| 结构式 |  |
(R)-Praziquantel-d11 性质
| 熔点 | 109 - 112°C |
|---|---|
| 储存条件 | -20°C Freezer |
| 溶解度 | 可溶于氯仿（少许）、DMSO（少许） |
| 形态 | 固体 |
| 颜色 | 白色至类白色 |
(R)-Praziquantel D11 是 (R)-Praziquantel 的氘代物。(R)-Praziquantel 是 Praziquantel 的活性对映体，是一种人 5-HT2B 受体的部分激动剂。(R)-Praziquantel 用作驱虫药，抗血吸虫。
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5-HT 2B Receptor
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Antischistosomal
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(R)-Praziquantel ((R)-PZQ) is a G-protein-coupled receptor ligand. (R)-Praziquantel modulation of serotoninergic signaling occurs over a concentration range sufficient to regulate vascular tone of the mesenteric blood vessels where the adult parasites reside within their host. The important anthelmintic is supported by a broad, cross species polypharmacology with (R)-Praziquantel modulating signaling events in both host and parasite.