(R)-Praziquantel-d11
| 中文名称 | (R)-Praziquantel-d11 |
|---|---|
| 中文同义词 | (R)-吡喹酮-D11;(R)-吡喹酮-D11(吡喹酮杂质4) |
| 英文名称 | (R)-Praziquantel-d11 |
| 英文同义词 | (R)-Praziquantel-d11;Binimetinib Impurity 8;Binimetinib Impurity |
| CAS号 | 1399880-38-6 |
| 分子式 | C19H24N2O2 |
| 分子量 | 312.41 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1399880-38-6.mol |
| 结构式 |  |
(R)-Praziquantel-d11 性质
| 熔点 | 109 - 112°C |
|---|---|
| 储存条件 | -20°C Freezer |
| 溶解度 | 可溶于氯仿（少许）、DMSO（少许） |
| 形态 | 固体 |
| 颜色 | 白色至类白色 |
(R)-Praziquantel D11 是 (R)-Praziquantel 的氘代物。(R)-Praziquantel 是 Praziquantel 的活性对映体，是一种人 5-HT2B 受体的部分激动剂。(R)-Praziquantel 用作驱虫药，抗血吸虫。
|
5-HT 2B Receptor
|
Antischistosomal
|
(R)-Praziquantel ((R)-PZQ) is a G-protein-coupled receptor ligand. (R)-Praziquantel modulation of serotoninergic signaling occurs over a concentration range sufficient to regulate vascular tone of the mesenteric blood vessels where the adult parasites reside within their host. The important anthelmintic is supported by a broad, cross species polypharmacology with (R)-Praziquantel modulating signaling events in both host and parasite.