- Br-PEG6-OH
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- $0.00 / 5g
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2024-03-25
- CAS:136399-05-8
- Min. Order: 5g
- Purity: >98.00%
- Supply Ability: 5g
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| Bromo-PEG6-alcohol Basic information |
Product Name: | Bromo-PEG6-alcohol | Synonyms: | Bromo-PEG6-alcohol;BROMO-PEG6-ALCOHOL; 17-BROMO-3,6,9,12,15-PENTAOXA-1-HEPTADECANOL;17-bromo-3,6,9,12,15-pentaoxa-1-heptadecanol;Br-PEG6-OH;3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-bromo-;Br-PEG6-OH,Bromo-PEG6-alcohol;17-Bromo-3,6,9,12,15-pentaoxaheptadecan-1-ol;Bromo-PEG6-alcohol,Br-PEG6-OH,Br-PEG6-alcohol | CAS: | 136399-05-8 | MF: | C12H25BrO6 | MW: | 345.23 | EINECS: | | Product Categories: | | Mol File: | 136399-05-8.mol |  |
| Bromo-PEG6-alcohol Chemical Properties |
Boiling point | 404.9±40.0 °C(Predicted) | density | 1.282±0.06 g/cm3(Predicted) | solubility | Soluble in Water, DCM | pka | 14.36±0.10(Predicted) | form | Liquid | color | Colorless to light yellow |
| Bromo-PEG6-alcohol Usage And Synthesis |
Description | Bromo-PEG6-alcohol is a PEG linker containing a bromide group and a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. | Uses | Bromo-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | IC 50 | PEGs | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| Bromo-PEG6-alcohol Preparation Products And Raw materials |
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