| Company Name: |
Amatek Scientific Co. Ltd.
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| Tel: |
0512-56316828 |
| Email: |
info@amateksci.com |
| Products Intro: |
Product Name:FmocNH-PEG3-CH2CH2N3
CAS:1172605-58-1
Purity:97% HPLC Package:1g;5g;25g;100g
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| Company Name: |
Suzhou Rovathin Foreign Trade Co.,Ltd
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| Tel: |
0512-65816829 18662214788 |
| Email: |
info@rovathin.com.cn |
| Products Intro: |
Product Name:13-Azido-5,8,11-trioxa-2-azatridecanoic acid 9H-fluoro-9-yl methyl ester
CAS:1172605-58-1
Purity:0.95 Package:1g;10g;100g;1kg
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| Company Name: |
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
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| Tel: |
meitaochem@126.com |
| Email: |
meitaochem@126.com |
| Products Intro: |
Product Name:13-Azido-5,8,11-trioxa-2-azatridecanoic acid 9H-fluoro-9-yl methyl ester
CAS:1172605-58-1
Purity:99% HPLC Package:50G；100G;
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| | 13-zido-,,1-rioxa--zatridecanoic acid 9H-luoren--lmethyl ester Basic information |
| Product Name: | 13-zido-,,1-rioxa--zatridecanoic acid 9H-luoren--lmethyl ester | | Synonyms: | 13-zido-,,1-rioxa--zatridecanoic acid 9H-luoren--lmethyl ester;13-Azido-5,8,11-trioxa-2-azatridecanoic acid 9H-fluoro-9-yl methyl ester;FmocNH-PEG3-CH2CH2N3;FmocNH-PEG3-CH2CH2N3/5,8,11-Trioxa-2-azatridecanoic acid, 13-azido-, 9H-fluoren-9-ylmethyl ester | | CAS: | 1172605-58-1 | | MF: | C23H28N4O5 | | MW: | 440.5 | | EINECS: | | | Product Categories: | | | Mol File: | 1172605-58-1.mol |  |
| | 13-zido-,,1-rioxa--zatridecanoic acid 9H-luoren--lmethyl ester Chemical Properties |
| | 13-zido-,,1-rioxa--zatridecanoic acid 9H-luoren--lmethyl ester Usage And Synthesis |
| Biological Activity | Fmoc-N-amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | 13-zido-,,1-rioxa--zatridecanoic acid 9H-luoren--lmethyl ester Preparation Products And Raw materials |
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