| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:6(S)-Lipoxin A4
CAS:94292-80-5
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:5(S),6(S)-Lipoxin A4
CAS:94292-80-5
Purity:95% Package:25μg;50μg;100μg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:6(S)-Lipoxin A4
CAS:94292-80-5
Purity:详情请点击官网 Package:1 mg
|
| Company Name: |
Cayman Chemical Company
|
| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Product Name:6(S)-Lipoxin A4
CAS:94292-80-5
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|
| | 6(S)-Lipoxin A4 Basic information |
| Product Name: | 6(S)-Lipoxin A4 | | Synonyms: | 6(S)-Lipoxin A4;IXAQOQZEOGMIQS-UZDWIPAXSA-N;7,9,11,13-Eicosatetraenoic acid, 5,6,15-trihydroxy-, (5S,6S,7E,9E,11Z,13E,15S)- | | CAS: | 94292-80-5 | | MF: | C20H32O5 | | MW: | 352.47 | | EINECS: | | | Product Categories: | | | Mol File: | 94292-80-5.mol |  |
| | 6(S)-Lipoxin A4 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml |
| | 6(S)-Lipoxin A4 Usage And Synthesis |
| Description | The lipoxins are trihydroxy fatty acids containing a 7,9,11,13-conjugated tetraene. Lipoxin A4 (LXA4) was first described as a metabolite of 15-HpETE and/or 15-HETE when added in vitro to isolated human leukocytes. The material obtained in this manner consists of at least four distinct isomers: 5(S), 6(S); 5(S), 6(R); and the 11-trans and 11-cis isomers of each of these. 6(S)-LXA4 is one of the original four metabolites first identified by Serhan, Nicolaou, and Samuelsson. It was considered to be an artifact by these authors because it lacked the potency of the 5(S),6(R) isomer with respect to contraction of isolated guinea pig lung parenchymal strips. It has not been possible to isolate “natural” LXA4 from humans or other mammals in amounts sufficient for determination of absolute stereochemistry. Most authors refer to LXA4 as the 5(S),6(R), 11-cis isomer, but it is not clear that biological systems are aware of or agree with these conventions. Historically, conjugated tetraenes flanked by hydroxyl groups of mixed stereochemistry have been marketed as ''Lipoxin A4'' by some biomolecular supply companies. The availability of single pure LXA4 enantiomers should help to reduce the confusion this has caused. | | Definition | ChEBI: 6-epi-lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6S)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds. It has a role as a metabolite. It is a lipoxin, a long-chain fatty acid and a hydroxy polyunsaturated fatty acid. |
| | 6(S)-Lipoxin A4 Preparation Products And Raw materials |
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