| Company Name: |
BOC Sciences
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1-631-485-4226; 16314854226 |
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info@bocsci.com |
| Products Intro: |
Product Name:YUKA1
CAS:708991-09-7
Purity:99% Remarks:YUKA1 is a cell-permeable inhibitor of lysine demethylase 5A (KDM5A/RBP2/JARID1A) (IC50 value 2.66 μM). YUKA1 inhibits drug resistance and cancer cell growth in HeLa cervical cancer cells and ZR-75-1
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| Product Name: | YUKA1 | | Synonyms: | YUKA1;3H-1,2,4-Triazole-3-thione, 2,4-dihydro-4-[[[3-methoxy-2-(2-propen-1-yloxy)phenyl]methyl]amino]-;YUKA1,YUKA-1 | | CAS: | 708991-09-7 | | MF: | C13H16N4O2S | | MW: | 292.36 | | EINECS: | | | Product Categories: | | | Mol File: | 708991-09-7.mol |  |
| | YUKA1 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | color | White to off-white |
| | YUKA1 Usage And Synthesis |
| Description | YUKA1 is a cell permeable, potent inhibitor of KDM5A, showing little to no activity against KDM5B, KDM6A, and KDM6B. YUKA1 was shown to increase H3K4me3 levels in human cells and selectively inhibit the proliferation of cancer cells whose growth depends on KDM5A. |
| | YUKA1 Preparation Products And Raw materials |
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