| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-Protein Disulfide Isomerase
Purity:IgG fraction of antiserum, buffered aqueous solution Package:200μL Remarks:P7496
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| | ANTI-PDI Basic information |
| Product Name: | ANTI-PDI | | Synonyms: | ANTI-PDI RABBIT PAB;ANTI-ERP58;Anti-Protein Disulfide Isomerase antibody produced in rabbit;Anti-Erp58, Anti-PDI;Anti-Protein Disulfide Isomerase (DL-11) antibody produced in rabbit;Anti-Protein Disulfide Isomerase (MD-12) antibody produced in rabbit;Anti-pancreatic protein disulfide isomerase;Anti-PDIA2 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-PDI Structure]() |
| | ANTI-PDI Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| Hazard Codes | Xn | | Risk Statements | 21/22 | | Safety Statements | 36/37 | | WGK Germany | 3 |
| | ANTI-PDI Usage And Synthesis |
| Uses | Anti-Protein Disulfide Isomerase (MD-12) antibody produced in rabbit has been used in:
- immunoblotting
- immunoprecipitation
- immunofluorescence
| | Uses | Anti-Protein Disulfide Isomerase antibody produced in rabbit has been used in immunoblotting, immunoprecipitation and immunofluorescence. | | Uses | Anti-Protein Disulfide Isomerase (DL-11) antibody produced in rabbit has been used in:
- immunofluorescence
- immunoprecipitation
- immunoblotting
| | General Description | Protein Disulfide Isomerase is an abundant multifunctional, soluble enzyme (E.C. 5.3.4.1). PDI is expressed in cellular localizations such as the cell surface, cytosol and nucleus. PDI consists of four tandem domains, two of which contain a catalytic site for S-S bond formation. One domain is the main site of noncovalent interaction with other peptides or proteins. PDI has an N-terminal ER signal and C-terminal ER retention KDEL signal sequences. | | Biochem/physiol Actions | Prolyl 4-hydroxylase subunit β (P4HB) acts as a molecular chaperone in the endoplasmic reticulum of cells and also as an oxidoreductase. It associates with steroid hormones and modulates their actions, concentrations and storage. P4HB accelerates the formation of disulphide bonds in proteins and hence aids in their folding. |
| | ANTI-PDI Preparation Products And Raw materials |
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