| Company Name: |
GL Biochem (Shanghai) Ltd
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| Tel: |
21-61263452 13641803416 |
| Email: |
ymbetter@glbiochem.com |
| Products Intro: |
Product Name:rec IL-4 (human)
Purity:95% HPLC,98% HPLC Package:10mg, 25mg, 50mg, 100mg, 500mg, 1g,10g
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| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:IL-4 human
Purity:recombinant, expressed in E. coli, >=98% (SDS-PAGE), >=98% ( Package:10UG Remarks:SRP4137-10UG
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| | HUMAN IL-4 Basic information |
| Product Name: | HUMAN IL-4 | | Synonyms: | RHIL-4;RECOMBINANT HUMAN IL-4;HUMAN BCGF;HUMAN BCDF;HUMAN BSF-1;INTERLEUKIN-4, HUMAN, RECOMBINANT;INTERLEUKIN-4, HUMAN, RECOMBINANT, E COLI;INTERLEUKIN-4, HUMAN | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![HUMAN IL-4 Structure]() |
| | HUMAN IL-4 Chemical Properties |
| storage temp. | -20°C | | form | lyophilized powder | | color | white |
| | HUMAN IL-4 Usage And Synthesis |
| Uses | IL-4 (interleukin 4) has been used to polarize the human monocytic leukemia (THP-1) cells to M2-like phenotype. | | Uses | Lymphokine with profound effects on the growth and differentiation of immunologically competent cells, inhibits VEGF-induced and βFGF-induced angiogenesis. | | Uses | Interleukin-4 (IL-4) has been used as a stimulant of M2 state of microglia that is associated with wound healing and debris clearance. | | General Description | IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant human IL-4 is a 14.9 kDa globular protein containing 129 amino acid residues. | | Biochem/physiol Actions | IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Recombinant human IL-4 is a 14.9 kDa globular protein containing 129 amino acid residues. |
| | HUMAN IL-4 Preparation Products And Raw materials |
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