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BOC Sciences
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Product Name:VU0071063 CAS:333415-38-6 Purity:98% Package:1G;10G;100G Remarks:VU0071063 is a potent and selective Kir6.2/SUR1 potassium channel activator. It inhibits glucose-stimulated calcium entry in isolated mouse pancreatic β-cells.
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Pharmacodia (Beijing) Co.,Ltd
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Product Name:VU0071063 CAS:333415-38-6 Package:10Mg-100g
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| 7-(4-TERT-BUTYLBENZYL)-1,3-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE Basic information |
Product Name: | 7-(4-TERT-BUTYLBENZYL)-1,3-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE | Synonyms: | 7-(4-TERT-BUTYLBENZYL)-1,3-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE;TOSLAB 808036;7-[[4-(1,1-Dimethylethyl)phenyl]methyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione;VU0071063;1H-Purine-2,6-dione, 7-[[4-(1,1-dimethylethyl)phenyl]methyl]-3,7-dihydro-1,3-dimethyl-;7-(4-(tert-butyl)benzyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione;Hyperpolarization,KcsA,Potassium Channel,Alzheimer,inhibit,B-cell,Specific,Potent,VU0071063,Insulin,Inhibitor | CAS: | 333415-38-6 | MF: | C18H22N4O2 | MW: | 326.39 | EINECS: | | Product Categories: | | Mol File: | Mol File | |
| 7-(4-TERT-BUTYLBENZYL)-1,3-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE Chemical Properties |
storage temp. | 2-8°C | solubility | DMSO: soluble10mg/mL, clear | form | powder | color | white to beige |
| 7-(4-TERT-BUTYLBENZYL)-1,3-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE Usage And Synthesis |
Description | VU0071063 is a potent and selective activator of the inward-rectifier potassium channel (Kir) 6.2 and sulfonylurea receptor (SUR) 1 (EC50 = 7 μM using whole cell patch clamp electrophysiology). It is selective for SUR1-containing Kir6.1 or Kir6.2 channels over SUR2A, Kir2.1, Kir2.2, Kir2.3, Kir3.1/3/2, and voltage-gated potassium channel 2.1. VU0071063 inhibits glucose-stimulated calcium entry in isolated mouse pancreatic β-cells. | storage | Store at -20°C |
| 7-(4-TERT-BUTYLBENZYL)-1,3-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE Preparation Products And Raw materials |
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