Azido-PEG3-Val-Cit-PAB-PNP manufacturers
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| Azido-PEG3-Val-Cit-PAB-PNP Basic information |
| Azido-PEG3-Val-Cit-PAB-PNP Chemical Properties |
solubility | Soluble in DMSO, DMF | form | Solid | color | White to light yellow |
| Azido-PEG3-Val-Cit-PAB-PNP Usage And Synthesis |
Description | Azido-PEG3-Val-Cit-PAB-PNP is a cleavable peptide ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. PNP groupg is a good leaving group when treating with aminebearing payload. Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility. |
| Azido-PEG3-Val-Cit-PAB-PNP Preparation Products And Raw materials |
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