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| | ANTI-ZAP-70 Basic information |
| | ANTI-ZAP-70 Chemical Properties |
| storage temp. | −20°C | | form | buffered aqueous solution |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 |
| | ANTI-ZAP-70 Usage And Synthesis |
| General Description | This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. (provided by RefSeq) |
| | ANTI-ZAP-70 Preparation Products And Raw materials |
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