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| | ANTI-FADD Basic information |
| Product Name: | ANTI-FADD | | Synonyms: | ANTI-TNFRSF 6 (DD) (HUMAN);ANTI-APO-1 (DD) (HUMAN);ANTI-CD95 (DD) (HUMAN);ANTI-FAS (DD) (HUMAN);ANTI-FAS ASSOCIATED DEATH DOMAIN;ANTI-FAS-ASSOCIATED DEATH DOMAIN PROTEIN;ANTI-FADD (DD);ANTI-FADD | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-FADD Structure]() |
| | ANTI-FADD Chemical Properties |
| storage temp. | −20°C | | form | buffered aqueous solution |
| | ANTI-FADD Usage And Synthesis |
| General Description | The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. (provided by RefSeq) |
| | ANTI-FADD Preparation Products And Raw materials |
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