Company Name: |
Sigma-Aldrich
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Tel: |
021-61415566 800-8193336 |
Email: |
orderCN@merckgroup.com |
Products Intro: |
Product Name:Protein Disulfide Isomerase from bovine liver CAS:37318-49-3 Purity:>95% (SDS-PAGE), >=100 units/mg protein, lyophilized powder Package:250UG Remarks:P3818-250UG
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Company Name: |
Nanjing Peptide Biotech Ltd.
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Tel: |
025-025-58361106-805-805 13082558573 |
Email: |
liugang@njpeptide.com |
Products Intro: |
Product Name:Protein disulfide-isomerase CAS:37318-49-3 Purity:90%HPLC,95%HPLC,98%HPLC Package:5mg,20mg,100mg,250mg,500mg,1g
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Company Name: |
Guangzhou Tomums Life Science Co., Ltd.
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Tel: |
020-31155029 18902330969 |
Email: |
sales@tomums.cn |
Products Intro: |
Product Name:Protein Disulfide Isomerase from bovine liver CAS:37318-49-3 Package:0.1MG;250UG
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| EC 5.3.4.1 Basic information |
Product Name: | EC 5.3.4.1 | Synonyms: | EC 5.3.4.1;CONNECTASH(TM) PROTEIN DISULFIDE-ISOMERASE;PROTEIN DISULFIDE ISOMERASE;THIOL:DISULFIDE INTERCHANGE PROTEIN DSBA;Protein disulfide Isomerase bovine liver;protein disulfide isomerase from E. coli;PROTEIN DISULFIDE ISOMERASE, FROM BOVINE LIVER;Recombinant Disulfide Oxidoreductase | CAS: | 37318-49-3 | MF: | C7H5Cl2NO5S | MW: | 0 | EINECS: | | Product Categories: | enzyme | Mol File: | Mol File | |
| EC 5.3.4.1 Chemical Properties |
storage temp. | -20°C | form | lyophilized powder |
WGK Germany | 3 | F | 3-10-21 | HS Code | 3504009000 |
| EC 5.3.4.1 Usage And Synthesis |
Uses | Protein Disulfide Isomerase from bovine liver has been used:
- to study the functional role of PDI in parasite infection and the interaction between macrophage PDI and?L. chagasi
- in the in vitro translation reaction for the generation of disulfide bonds
- in insulin-disulfide reduction assay and peptide binding assay
- as a positive control in thiol-disulfide oxidoreductase activity assay
| General Description | Protein disulfide isomerase (PDI) from bovine liver is a homodimer with a molecular weight of 107 kDa with the monomer corresponding to 57 kDa. The isoelectric point (pI) is approximately 4.2. The enzyme is a glycoprotein with 12% total carbohydrate content comprising of mannose, galactose, N-acetyl neuraminic acid (NANA) and 2-acetamido-2-deoxyglucose. PDI is an ubiquitous redox chaperone enzyme. It belongs to the, thioredoxin superfamily and is high conserved. | Biochem/physiol Actions | Protein Disulfide Isomerase (PDI) is mainly located in the endoplasmic reticulum (ER), where it assists in protein-folding and thiol-disulfide exchanges. It aids protein refolding in vitro allowing recombinant proteins to achieve their native state. |
| EC 5.3.4.1 Preparation Products And Raw materials |
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