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11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID

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11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:CAY10410
CAS:596104-94-8
Package:1mg;397USD
Company Name: Dalian Meilun Biotech Co., Ltd.  
Tel: 0411-62910999 13889544652
Email: meilunui@163.com
Products Intro: Product Name:CAY-10410
CAS:596104-94-8
Purity:>98%,BR Package:1MG Remarks:MB6151
Company Name: BOC Sciences  
Tel: 16314854226
Email: info@bocsci.com
Products Intro: Product Name:CAY10410
CAS:596104-94-8
Purity:98% (isomer mixture) Package:1G;10G;100G Remarks:CAY10410 is an analog of prostaglandin D2/prostaglandin J2 (PGD2/PGJ2) with structural modifications intended to give it PPARγ ligand activity and resistance to metabolism. It was designed as an analo
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Tel: 400-9205774
Email: sales@glpbio.cn
Products Intro: Product Name:CAY10410
CAS:596104-94-8
Purity:>98% Package:1mg;10mg;50mg;100mg;
Company Name: Hangzhou Synstar pharmaceutical Technology CO.,Ltd  
Tel: 0571-85361029
Email: synstar518@163.com
Products Intro: Product Name:9,10-dihydro-15-deoxy-delta12,14-Prostaglandin J2
CAS:596104-94-8
Purity:0.98 Package:100mg、500mg、1g、5g

11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID manufacturers

  • CAY10410
  • CAY10410 pictures
  • $397.00 / 1mg
  • 2024-10-28
  • CAS:596104-94-8
  • Min. Order:
  • Purity:
  • Supply Ability: 10g
11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID Basic information
Product Name:11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID
Synonyms:11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID;9,10-DIHYDRO-15-DEOXY-DELTA12,14-PROSTAGLANDIN J2;CAY10410;9,10-dihydro-15-deoxy-Δ12,14-Prostaglandin J2;AFBJLDUEEOOVHL-WKELIDJCSA-N;Prosta-5,12,14-trien-1-oic acid, 11-oxo-, (5Z,12E,14Z)-;CAY10410,CAY-10410
CAS:596104-94-8
MF:C20H30O3
MW:318.45
EINECS:
Product Categories:
Mol File:Mol File
11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID Structure
11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID Chemical Properties
storage temp. Store at -20°C
solubility DMF: 100 mg/ml; DMSO: 20 mg/ml; Ethanol: 75 mg/ml; PBS (7.2): 2.7 mg/ml
Safety Information
MSDS Information
11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID Usage And Synthesis
DescriptionCAY10410 is an analog of prostaglandin D2/prostaglandin J2 (PGD2/PGJ2) with structural modifications intended to give it PPARγ ligand activity and resistance to metabolism. 15-deoxy-Δ12,14-PGJ2 has been shown to be a potent ligand for PPARγ.1 Metabolism of the cyclopentenone prostaglandins PGA2, PGJ2, and Δ12-PGJ2 occurs via glutathione addition across the α,β unsaturated enone.2 CAY10410 was designed as an analog of the PPARγ-binding prostaglandins which could not undergo this conjugation reaction. In human neuroblastoma SH-SY5Y cells, CAY10410 was not cytotoxic at up to 25 μM. It also failed to covalently modify thioredoxin or induce oxidative stress at 50 μM.3
References1. Forman, B.M., Tontonoz, P., Chen, J., et al. 15-Deoxy-Δ12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ Cell 83(5),803-812(1995).
2. Atsmon, J., Sweetman, B.J., Baertschi, S.W., et al. Formation of thiol conjugates of 9-deoxy-Δ9,Δ12(E)-prostaglandin D2 and Δ12(E)-prostaglandin D2 Biochemistry 29,3760-3765(1990).
3. Shibata, T., Yamada, T., Ishii, T., et al. Thioredoxin as a molecular target of cyclopentenone prostaglandins J. Biol. Chem. 278(28),26046-26054(2003).
11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID Preparation Products And Raw materials
Tag:11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID(596104-94-8) Related Product Information
PROSTAGLANDIN J2