Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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Tel: |
821-50328103-801 18930552037 |
Email: |
3bsc@sina.com |
Products Intro: |
Product Name:3-MPPI;2-[(4-Phenylpiperazin-1-yl)Methyl]-2,3-dihydroiMidazo[1,2-c]quinazolin-5(6H)-one Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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Company Name: |
BOC Sciences
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Tel: |
1-631-485-4226; 16314854226 |
Email: |
info@bocsci.com |
Products Intro: |
Product Name:2-PMDQ CAS:139047-55-5 Remarks:2-PMDQ, an analog of Ketanserin with beneficial hemodynamic effects in portal hypertensive rats, is a potent and selective α1-adrenoceptor antagonist.
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Company Name: |
EMMX Biotechnology LLC
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Tel: |
888-539-0666 |
Email: |
info@emmx.com |
Products Intro: |
Product Name:2-PMDQ CAS:139047-55-5 Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| 2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Basic information |
| 2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Chemical Properties |
density | 1.35±0.1 g/cm3(Predicted) | storage temp. | Store at RT | solubility | Soluble to 10 mM in DMSO and in ethanol | form | Powder | pka | 13.74±0.40(Predicted) |
| 2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Usage And Synthesis |
Uses | 2-PMDQ is an analog of Ketanserin with beneficial hemodynamic effects in portal hypertensive rats. Anti-hypertensive effects. | Definition | ChEBI: 2-[(4-phenyl-1-piperazinyl)methyl]-3,6-dihydro-2H-imidazo[1,2-c]quinazolin-5-one is a member of piperazines. | Biological Activity | Very potent ligand for α 1 sites (K i for displacement of prazosin = 0.2 nM). Also binds to 5-HT 1A sites (K i = 50 nM). |
| 2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Preparation Products And Raw materials |
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