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Shanghai Massive Chemical Technology Co., Ltd.
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Product Name:4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile
CAS:939431-68-2
Purity:98% Package:25KG；5KG；1KG
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| | 4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile Basic information |
| Product Name: | 4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile | | Synonyms: | 4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile;Etravirine Impurity 12;4-[[6-amino-2-(4-cyanoanilino)-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile;Benzonitrile, 4-[[6-amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-;4-[[6-Amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile | | CAS: | 939431-68-2 | | MF: | C20H16N6O | | MW: | 356.38 | | EINECS: | 458-850-7 | | Product Categories: | | | Mol File: | 939431-68-2.mol | ![4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile Structure](CAS/20180713/GIF/939431-68-2.gif) |
| | 4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile Chemical Properties |
| Melting point | 284.5-287 °C | | Boiling point | 632.1±65.0 °C |
| | 4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile Usage And Synthesis |
| Uses | 4-[[6-Amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile is an impurity of Etravirine (E937000), which is a novel HIV reverse transcriptase inhibitor useful in treatment of HIV infection. It can be used as a novel HIV-1 NNRTIs by using its hydrophobic channel and tolerant regions of NNIBP. It can also be used to synthesize etravirine, a non-nucleoside reverse transcriptase inhibitor. |
| | 4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile Preparation Products And Raw materials |
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