| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-NGFR
Purity:Prestige Antibody pow Package:100μL Remarks:HPA004765
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| | ANTI-NERVE GROWTH FACTOR RECEPTOR Basic information |
| Product Name: | ANTI-NERVE GROWTH FACTOR RECEPTOR | | Synonyms: | NERVE GROWTH FACTOR RECEPTOR (P75LANGFR) (AB-1) MONOCLONAL ANTIBODY;MOUSE ANTI-HUMAN/PORCINE/CANINE/FELINE/PRIMATE/RABBIT/RACCOON NERVE GROWTH FACTOR RECEPTOR, LOW AFFINITY P75;ANTI-TNFRSE 16;ANTI-NGF-R;ANTI-NGF-RECEPTOR;ANTI-NGF RECEPTOR (AB-1);ANTI-NERVE GROWTH FACTOR RECEPTOR (NGFR P75), HUMAN;ANTI-NERVE GROWTH FACTOR RECEPTOR | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-NERVE GROWTH FACTOR RECEPTOR Structure]() |
| | ANTI-NERVE GROWTH FACTOR RECEPTOR Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous glycerol solution |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 |
| | ANTI-NERVE GROWTH FACTOR RECEPTOR Usage And Synthesis |
| Uses | All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit . | | General Description | NGFR (nerve growth factor receptor) is a cell surface transmembrane glycoprotein. It belongs to the low-affinity neurotrophin receptor and tumor necrosis factor receptor superfamily. It is expressed on the surface of glial fibrillary acidic protein δ (GFAPδ) cells of the human brain. In addition to the brain, it is also expressed in liver, lung, and muscle cells. | | Biochem/physiol Actions | NGFR (nerve growth factor receptor) plays a crucial role in the neuronal survival, differentiation and development of neurons in adult brain. It has been reported that the membrane-spanning region and cytoplasmic domain of NGFR plays an essential role in signal transduction during neuronal differentiation. In CNS and peripheral tissues, NGFR acts as a clock gene and its activity is modulated by helix-loop-helix transcription factors: CLOCK and BMAL1. |
| | ANTI-NERVE GROWTH FACTOR RECEPTOR Preparation Products And Raw materials |
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