| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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400-9205774 |
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sales@glpbio.cn |
| Products Intro: |
Product Name:Padanamide A
CAS:1314881-80-5
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Padanamide A
CAS:1314881-80-5
Purity:95% Package:1mg;5mg
|
| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.com |
| Products Intro: |
Product Name:Padanamide A
CAS:1314881-80-5
Purity:详情请点击官网 Package:1 mg
|
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| | Padanamide A Basic information |
| Product Name: | Padanamide A | | Synonyms: | Padanamide A;(S)-N-((2S,3S,4S)-5-(((S)-1-carbamoyl-2-oxopyrrolidin-3-yl)amino)-3-hydroxy-4-methyl-5-oxo-1-phenylpentan-2-yl)-2-((2R,3R)-3-hydroxy-2-(2-methoxyacetamido)-4-methylpentanoyl)hexahydropyridazine-3-carboxamide | | CAS: | 1314881-80-5 | | MF: | C31H47N7O9 | | MW: | 661.74638 | | EINECS: | | | Product Categories: | | | Mol File: | 1314881-80-5.mol |  |
| | Padanamide A Chemical Properties |
| density | 1.34±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | | form | A solid | | pka | 13.24±0.46(Predicted) |
| | Padanamide A Usage And Synthesis |
| Description | Padanamide A is a bacterial metabolite originally isolated from a marine Streptomyces species.1 It is active against five strains of P. falciparum (EC50s = 160-340 nM), is not cytotoxic to HEK293 or HepG2 human cell lines, but is cytotoxic to Jurkat T lymphocytes with an IC50 value of approximately 60 μg/ml.2,3 | | References | 1. Nam, S.J., Kauffman, C.A., Jensen, P.R., et al. Isolation and characterization of actinoramides A-C, highly modified peptides from a marine Streptomyces sp Tetrahedron 67(35),6707-6712(2011).
2. Cheng, K.-C., Cao, S., Raveh, A., et al. Actinoramide A identified as a potent antimalarial from titration-based screening of marine natural product extracts J. Nat. Prod. 78(10),2411-2422(2015).
3. Williams, D.E., Dalisay, D.S., Patrick, B.O., et al. Padanamides A and B, highly modified linear tetrapeptides produced in culture by a Streptomyces sp. isolated from a marine sediment Org. Lett. 13(15),3936-3939(2011). |
| | Padanamide A Preparation Products And Raw materials |
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