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Product Name:C18 Globotriaosylceramide (d18:1/18:0)
CAS:69283-33-6
Purity:98+% Package:500ug
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Alfa Chemistry
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Product Name:C18 Globotriaosylceramide (d18:1/18:0)
CAS:69283-33-6
Purity:98%+ Package:1g;10g;100g;1KG;5KG
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| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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sales@glpbio.cn |
| Products Intro: |
Product Name:C18 Globotriaosylceramide (d18:1/18:0)
CAS:69283-33-6
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| | C18 Globotriaosylceramide (d18:1/18:0) Basic information |
| Product Name: | C18 Globotriaosylceramide (d18:1/18:0) | | Synonyms: | C18 Globotriaosylceramide (d18:1/18:0);Octadecanoyl-ceramide trihexoside;Octadecanamide, N-[(1S,2R,3E)-1-[[(O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl)oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]-;N-Octadecanoyl-ceramide trihexoside | | CAS: | 69283-33-6 | | MF: | C54H101NO18 | | MW: | 1052.37564 | | EINECS: | | | Product Categories: | | | Mol File: | 69283-33-6.mol |  |
| | C18 Globotriaosylceramide (d18:1/18:0) Chemical Properties |
| Boiling point | 1132.1±65.0 °C(Predicted) | | density | 1.22±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Chloroform:Methanol (2:1): Soluble; DMSO: Soluble; Methanol: Warmed | | form | A solid | | pka | 12.76±0.70(Predicted) |
| | C18 Globotriaosylceramide (d18:1/18:0) Usage And Synthesis |
| Description | C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide . It inhibits aggregation of human neutrophils induced by phorbol 12-myristate 13-acetate (PMA; 10008014) when used at a concentration of 1 μM. C18 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raji cells and THP-1 monocytes. It accumulates in the brain, heart, kidney, liver, lung, and spleen in a mouse model of Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme α-galactosidase A. C18 globotriaosylceramide also accumulates in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease. [Matreya, LLC. Catalog No. 1529] | | Definition | ChEBI: Alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1/18:0) is a glycotriaosylceramide having alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl as the glycotriaosyl component attached to the Cer(d18:1/18:0). It has a role as a mouse metabolite. It is functionally related to an octadecanoic acid. |
| | C18 Globotriaosylceramide (d18:1/18:0) Preparation Products And Raw materials |
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