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| | BCI-215 Basic information |
| Product Name: | BCI-215 | | Synonyms: | BCI-215;BCI-215
(BCI215;1H-Inden-1-one, 5-bromo-3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-, (2E)-;specificity,Phosphatase,DUSP-MKP,inhibit,Inhibitor,MAPK,BCI-215,BCI215,BCI 215,dual;(E)-2-Benzylidene-5-bromo-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one | | CAS: | 1245792-67-9 | | MF: | C22H22BrNO | | MW: | 396.32 | | EINECS: | | | Product Categories: | API | | Mol File: | 1245792-67-9.mol |  |
| | BCI-215 Chemical Properties |
| Boiling point | 523.0±50.0 °C(Predicted) | | density | 1.37±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 33.33 mg/mL (84.10 mM) | | form | Solid | | pka | 6.32±0.20(Predicted) | | color | White to light yellow |
| | BCI-215 Usage And Synthesis |
| Definition | ChEBI: BCI-215 is an aromatic ketone that is 2,3-dihydro-1H-inden-1-one which is substituted at positions 2, 3, and 5 by (E)-benzylidene, cyclohexylamino, and bromine, respectively. A hyperactivator of fibroblast growth factor signaling in transgenic zebrafish that is devoid of developmental toxicity and restores defective MAPK activity caused by overexpression of DUSP1 and DUSP6 in mammalian cells. It has a role as an antineoplastic agent and an apoptosis inducer. It is a secondary amino compound, an aromatic ketone, an organobromine compound, an enone and a member of indanones. |
| | BCI-215 Preparation Products And Raw materials |
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