Company Name: |
Guangzhou Younan Technology Co., Ltd
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Tel: |
020-020-82000279 18988968278 |
Email: |
sales@ubiochem.com |
Products Intro: |
Product Name:DSP-1053 CAS:1176326-76-3 Purity:98% Package:5mg;10mg;50mg;100mg
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Company Name: |
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
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Tel: |
021-59167510 18117107507 |
Email: |
vip@med-life.cn |
Products Intro: |
Product Name:DSP-1053 CAS:1176326-76-3 Purity:>=99% Package:10mg;100mg;10mM*1mLinDMSO;5mg;50mg
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| DSP-1053 Basic information |
Product Name: | DSP-1053 | Synonyms: | DSP-1053;4H-1-Benzopyran-4-one, 6-[2-[4-[[4-bromo-3-(2-methoxyethoxy)phenyl]methyl]-1-piperidinyl]ethyl]-2,3-dihydro- | CAS: | 1176326-76-3 | MF: | C26H32BrNO4 | MW: | 502.44 | EINECS: | | Product Categories: | | Mol File: | 1176326-76-3.mol | |
| DSP-1053 Chemical Properties |
Boiling point | 610.7±55.0 °C(Predicted) | density | 1.294±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMSO : 100 mg/mL (199.03 mM; Need ultrasonic) | form | Solid | pka | 9.06±0.10(Predicted) | color | Off-white to light yellow |
| DSP-1053 Usage And Synthesis |
Biological Activity | DSP-1053, a benzylpiperidine derivative, is a potent Serotonin Transporter (SERT) inhibitor with a Ki of 1.02 nM. DSP-1053 shows partial 5-HT1A receptor agonistic activity with a Ki of 5.05 nM. DSP-1053 has antidepressant activity[1]. | References | [1]. Yoshinaga H, et al. Discovery of DSP-1053, a novel benzylpiperidine derivative with potent serotonin transporter inhibitory activity and partial 5-HT1A receptor agonistic activity. Bioorg Med Chem. 2018 May 1;26(8):1614-1627. |
| DSP-1053 Preparation Products And Raw materials |
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