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| | GAT-211 Basic information |
| Product Name: | GAT-211 | | Synonyms: | GAT-211;3-(2-nitro-1-phenylethyl)-2-phenyl-1H-indole;1H-Indole, 3-(2-nitro-1-phenylethyl)-2-phenyl-;GAT211 >=98% (HPLC);AZ 4;AZ4;AZ-4 | | CAS: | 102704-40-5 | | MF: | C22H18N2O2 | | MW: | 342.39 | | EINECS: | | | Product Categories: | | | Mol File: | 102704-40-5.mol |  |
| | GAT-211 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 25 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml | | form | A crystalline solid | | color | White to off-white |
| | GAT-211 Usage And Synthesis |
| Description | GAT211, aslo known as AZ-4, is a small molecule CB1 positive allosteric modulator. GAT211 suppresses allodynia and produces synergistic antiallodynic effects with fatty acid amide hydrolase and monoacylglycerol lipase inhibitors in paclitaxel-treated mice. Positive allosteric modulation of CB1-receptor signaling with GAT211shows promise as a safe and effective analgesic strategy that lacks tolerance, dependence, and abuse liability. |
| | GAT-211 Preparation Products And Raw materials |
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