| Company Name: |
TRUE LABS
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| Tel: |
+91-9948900000 +91-8919325074 |
| Email: |
info@truelabs.in |
| Products Intro: |
Product Name:JAS-239
CAS:1630288-74-2
Purity:98% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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| | JAS239 Chemical Properties |
| | JAS239 Usage And Synthesis |
| Description | JAS239 is a novel carbocyanine dye that binds and competitively inhibits choline kinase (ChoK) intracellularly. JAS239 attenuated choline phosphorylation and viability in a panel of human breast cancer cell lines. Antibody blockade prevented cellular retention of JAS239 indicating direct interaction with ChoKα independent of the choline transporters and catabolic choline pathways. In mice bearing orthotopic MCF7 breast xenografts, optical imaging with JAS239 distinguished tumors overexpressing ChoKα from their empty vector counterparts and delineated tumor margins. |
| | JAS239 Preparation Products And Raw materials |
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