| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Phalloidin, Fluorescein Isothiocyanate Labeled
Purity:peptide from Amanita phalloides Package:.1MG Remarks:P5282-.1MG
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| Company Name: |
Absin Bioscience Inc.
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| Tel: |
021-38015121 15000105423 |
| Email: |
chenjw@absin.cn |
| Products Intro: |
Product Name:FITC - PHALLOIDIN CONJUGATE
Purity:95% Package:1mg
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| Company Name: |
JiangSu Star Science Co.,Ltd
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| Tel: |
400-605-7200 17312445705 |
| Email: |
sales022@b2star.com |
| Products Intro: |
Product Name:Phalloidin, Fluorescein Isothiocyanate Labeled
Package:10g; 100g;500g;1kg;5KG;10KG
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| | FITC - PHALLOIDIN CONJUGATE Basic information |
| Product Name: | FITC - PHALLOIDIN CONJUGATE | | Synonyms: | FITC - PHALLOIDIN CONJUGATE;PHALLOIDIN (FITC);PHALLOIDIN-FITC LABELED;PHALLOIDIN - FLUORESCEIN ISOTHIOCYANATE CONJUGATE;Phalloidin, Fluorescein Isothiocyanate Labeled
| | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![FITC - PHALLOIDIN CONJUGATE Structure]() |
| | FITC - PHALLOIDIN CONJUGATE Chemical Properties |
| | FITC - PHALLOIDIN CONJUGATE Usage And Synthesis |
| Uses | Phalloidin, Fluorescein Isothiocyanate Labeled has been used:
- To visualize F-Actin reorganization in primary neonatal cardiomyocytes (PNCMs) and H9C2 cells (rat cardiac myoblasts) following endothelin-1 (ET-1) and angiotensin II (Ang II) treatment.
- In immunochemistry to label microfilament.
- In immunofluorescence analysis to stain F-actin.
| | General Description | Phalloidin is a phallotoxin produced by death cap mushroom Amanita phalloides. It is a cyclic peptide, which interacts with actin and this was first identified in phalloidin-poisoned rats. It is a heptapeptide, cyclic in nature, with a crosslink between tryptophan at position 6 and cysteine at position 3. The side chain of amino acid 7 (γ-δ-dihydroxyleucine) in phalloidin, is accessible to modifications, through which fluorescently labelled phalloidin compounds can be produced. | | Biochem/physiol Actions | Phalloidin interacts with polymeric actin, and not oligomeric or monomeric forms. This interaction leads to highly stabilized actin filaments, which resist depolymerization and disassembly. In rats, this toxin causes death due to liver hemorrhage, and cells show abnormal actin clustering. The affinity of phalloidin to actin is not significantly altered after derivatizing fluorescently labelled phalloidin compounds. These compounds can be used to study actin structure and organization within eukaryotic cells. |
| | FITC - PHALLOIDIN CONJUGATE Preparation Products And Raw materials |
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