β-CGRP, human TFA
| 中文名称 | β-CGRP, human TFA |
|---|---|
| 中文同义词 | Β-CGRP, HUMAN TFA |
| 英文名称 | β-CGRP, human TFA |
| 英文同义词 | β-CGRP, human TFA |
| CAS号 | |
| 分子式 | C???H???F?N??O??S? |
| 分子量 | 0 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | Mol File |
| 结构式 |
β-CGRP, human TFA 性质
| 形态 | 固体 |
|---|---|
| 颜色 | 白色至米白色 |
β-CGRP, human TFA (Human β-CGRP TFA) 是一种降钙素肽，通过降钙素受体样受体 CRLR 与 RAMP 的复合物起作用，在细胞体系中，对 CRLR/RAMP1 和 CRLR/RAMP2 的 IC50 值分别为 1 nM 和 300 nM。
IC50: 1 nM (CRLR/RAMP1, cell assay), 300 nM (CRLR/RAMP2, cell assay)
β-CGRP, human is one of calcitonin peptides, acts via complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC 50 s of 1 nM in both SK-N-MC and Swiss 3T3 cells express CRLR and RAMP1, and 130 nM and 300 nM in NG108-15 and HEK293T cells expressing CRLR and RAMP2. CGRP is a potent vasodilator and also shows pro- and -anti-inflammatory activity.