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ERK1/2 inhibitor 1

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Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:ERK1/2 inhibitor 1
CAS:2095719-90-5
Purity:99.09% Package:1mg;128USD|5mg;322USD|10mg;465USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:ERK1/2 inhibitor 1
CAS:2095719-90-5
Purity:99.09% Package:1mg;128USD|5mg;322USD|10mg;465USD
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:ERK1/2 inhibitor 1
CAS:2095719-90-5
Purity:99% Package:$650.9/5mg;$980.9/10mg;$2550.9/50mg;$3550.9/100mg;Bulk package Remarks:99%
Company Name: Shanghai Anyinuo Biomedical Technology Co., Ltd.  
Tel: 021-34625901
Email: 420970979@qq.com
Products Intro: Product Name:(R)-2-(6-(5-Chloro-2-((tetrahydro-2H-pyran-4-yl)amino)pyrimidin-4-yl)-1-oxoisoindolin-2-yl)-N-((S)-2-hydroxy-1-(m-tolyl)ethyl)propanamide
CAS:2095719-90-5
Purity:>=98% Package:100mg;250mg;500mg;1g;10g;100g;1kg
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Tel: 15911056312
Email: liming@bio-fount.com
Products Intro: Product Name:ERK1/2 inhibitor 1
CAS:2095719-90-5
Purity:97.0% Package:5mg

ERK1/2 inhibitor 1 manufacturers

  • ERK1/2 inhibitor 1
  • ERK1/2 inhibitor 1 pictures
  • $128.00 / 1mg
  • 2024-11-11
  • CAS:2095719-90-5
  • Min. Order:
  • Purity: 99.09%
  • Supply Ability: 10g
  • ERK1/2 inhibitor 1
  • ERK1/2 inhibitor 1 pictures
  • $128.00 / 1mg
  • 2024-11-11
  • CAS:2095719-90-5
  • Min. Order:
  • Purity: 99.09%
  • Supply Ability: 10g
ERK1/2 inhibitor 1 Basic information
Product Name:ERK1/2 inhibitor 1
Synonyms:ERK1/2 INHIBITOR 1;2H-Isoindole-2-acetamide, 6-[5-chloro-2-[(tetrahydro-2H-pyran-4-yl)amino]-4-pyrimidinyl]-1,3-dihydro-N-[(1S)-2-hydroxy-1-(3-methylphenyl)ethyl]-α-methyl-1-oxo-, (αR)-;ERK-1/2 inhibitor 1,ERK1/2 inhibitor 1;(R)-2-(6-(5-Chloro-2-((tetrahydro-2H-pyran-4-yl)amino)pyrimidin-4-yl)-1-oxoisoindolin-2-yl)-N-((S)-2-hydroxy-1-(m-tolyl)ethyl)propanamide
CAS:2095719-90-5
MF:C29H32ClN5O4
MW:550.06
EINECS:
Product Categories:
Mol File:2095719-90-5.mol
ERK1/2 inhibitor 1 Structure
ERK1/2 inhibitor 1 Chemical Properties
density 1.344±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 250 mg/mL (454.50 mM; Need ultrasonic)
pka13.73±0.46(Predicted)
form Solid
color Off-white to light yellow
Safety Information
MSDS Information
ERK1/2 inhibitor 1 Usage And Synthesis
Biological ActivityERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively[1]. ERK1/2 inhibitor 1 (Compound 27) shows excellent antiproliferative potency with IC50s of 4.9 and 7.5 nM in A375 and Colo205 cells, respectively[1].
References[1]. Heightman TD, et al. Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2. J Med Chem. 2018 Jun 14;61(11):4978-4992.
ERK1/2 inhibitor 1 Preparation Products And Raw materials
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