| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
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| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:Tazofelone, LY-213829
CAS:107902-67-0
Purity:≥98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
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| Company Name: |
Guangzhou Younan Technology Co., Ltd
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| Tel: |
020-020-82000279 18988968278 |
| Email: |
sales@ubiochem.com |
| Products Intro: |
Product Name:Tazofelone
CAS:107902-67-0
Purity:98% Package:5mg;10mg;50mg;100mg
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| Company Name: |
Bide Pharmatech Ltd.
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| Tel: |
400-1647117 13681763483 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:5-(3,5-Di-tert-butyl-4-hydroxybenzyl)thiazolidin-4-one
CAS:107902-67-0
Purity:98% Package:1mg;5mg;10mg;25mg;50mg Remarks:BD01153218
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| | Tazofelone, LY-213829 Basic information |
| Product Name: | Tazofelone, LY-213829 | | Synonyms: | Tazofelone, LY-213829;4-Thiazolidinone, 5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]-;LY-213829;5-(3,5-Di-tert-butyl-4-hydroxybenzyl)thiazolidin-4-one;Inhibitor,LY 213829,Tazofelone,CYP3A,inflammatory bowel disease,inhibit,Cyclooxygenase,COX,LY213829 | | CAS: | 107902-67-0 | | MF: | C18H27NO2S | | MW: | 321.48 | | EINECS: | | | Product Categories: | | | Mol File: | 107902-67-0.mol |  |
| | Tazofelone, LY-213829 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO : 100 mg/mL (311.06 mM; Need ultrasonic) | | form | Solid | | color | White to off-white |
| | Tazofelone, LY-213829 Usage And Synthesis |
| Biological Activity | Tazofelone (LY 213829) is a cyclooxygenase-II (COX-II) inhibitor. Tazofelone transform into sulfoxide and quinol metabolites is primarily mediated by CYP3A. Tazofelone can be used for the research of inflammatory bowel disease[1][2]. | | References | [1]. Leopold Franz Goetze,et al. Cox- ii inhibitors for improving reproductive success in a female animal. Patent: WO2007129169 A2. [2]. Surapaneni SS, et al. In vitro biotransformation and identification of human cytochrome P450 isozyme-dependent metabolism of tazofelone. Drug Metab Dispos. 1997 Dec;25(12):1383-8. |
| | Tazofelone, LY-213829 Preparation Products And Raw materials |
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