| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:SM-276001
CAS:473930-22-2
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| | SM-276001 Basic information |
| Product Name: | SM-276001 | | Synonyms: | SM-276001;immune,SM-276001,IFNAR,Interferon-alpha/beta receptor,IFN,Toll-like Receptor (TLR),SM276001,inhibit,TLR7,Inhibitor,Interferon-α/β receptor,interferon,SM 276001,antitumor;8H-Purin-8-one, 6-amino-2-(butylamino)-7,9-dihydro-9-[(6-methyl-3-pyridinyl)methyl]- | | CAS: | 473930-22-2 | | MF: | C16H21N7O | | MW: | 327.38 | | EINECS: | | | Product Categories: | | | Mol File: | 473930-22-2.mol |  |
| | SM-276001 Chemical Properties |
| Melting point | 248.5-252 °C(Solv: methanol (67-56-1)) | | density | 1.322±0.06 g/cm3(Predicted) | | pka | 10.30±0.20(Predicted) | | form | Solid | | color | Off-white to light yellow |
| | SM-276001 Usage And Synthesis |
| Description | SM-276001 is a selective and potent TLR7 agonist. SM-276001 is can induce antitumor immune responses when dosed either intratracheally or orally. Oral administration of SM-276001 leads to the induction of IFNα, TNFα and IL-12p40 and a reduction in tumor burden in the Balb/c syngeneic Renca and CT26 models. |
| | SM-276001 Preparation Products And Raw materials |
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