UCP2 (D1O5V) Rabbit mAb

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UCP2 (D1O5V) Rabbit mAb Suppliers list
Company Name: Shanghai Universal Biotech Co.,Ltd  
Tel: 15921930842 15921930842
Email: yh-wang@univ-bio.com
UCP2 (D1O5V) Rabbit mAb Basic information
Source Reactivity Background References
Product Name:UCP2 (D1O5V) Rabbit mAb
Synonyms:UCP2 (D1O5V) Rabbit mAb
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MW:0
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UCP2 (D1O5V) Rabbit mAb Structure
UCP2 (D1O5V) Rabbit mAb Chemical Properties
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UCP2 (D1O5V) Rabbit mAb Usage And Synthesis
SourceRabbit
ReactivityHuman;Mouse;Rat;Monkey
BackgroundUncoupling protein 2 is a mitochondrial inner membrane transport protein that is expressed in a wide range of tissues. UCP2 inhibits mitochondrial glucose oxidation and promotes glycolysis in human pluripotent stem cells. During early differentiation of hPSCs, the expression of UCP2 is repressed, which results in reduced glycolysis. This demonstrates a role for UCP2 in the metabolic reprogramming during differentiation of hPSCs. Overexpression of UCP2 in cancer cells stimulates oxidative phosphorylation in mitochondria and inhibits cell proliferation.
References[1] Mailloux, R.J. et al. (2011) J Biol Chem 286, 21865-75.
[2] Zhang, J. et al. (2011) EMBO J 30, 4860-73.
[3] Esteves, P. et al. (2014) Cancer Res 74, 3971-82.
UCP2 (D1O5V) Rabbit mAb Preparation Products And Raw materials
Tag:UCP2 (D1O5V) Rabbit mAb Related Product Information
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