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ANTI-TGN38

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ANTI-TGN38 Suppliers list
Company Name: Riedel-de Haen AG  
Tel: 800 558-9160
Email:
Products Intro: Remarks:~1 mg/mL, affinity isolated antibody, buffered aqueous solution
Company Name: Kanto Chemical Co., Inc.  
Tel: +81 3 3663 7631
Email: reag-info@gms.kanto.co.jp
Products Intro:
Company Name: Alexis Corporation  
Tel: +41 61 926 8989
Email: alexis-ch@alexis-corp.ch
Products Intro:
Company Name: ABR-Affinity BioReagents  
Tel: 303 278 4535
Email: affinity@bioreagents.com
Products Intro:
Company Name: BD Biosciences  
Tel: 1 877 232 8995 U.S. orders
Email:
Products Intro:
ANTI-TGN38 Basic information
Product Name:ANTI-TGN38
Synonyms:TRANS-GOLGI NETWORK 38 (AB-1) MONOCLONAL ANTIBODY;ANTI-TGN38;ANTI-TGN38 (RAT);ANTI-TRANS-GOLGI NETWORK 38;ANTI-TRANS-GOLGI NETWORK 38 (AB-1);ANTI-TRANS-GOLGI NETWORK 38 MOUSE MAB;ANTI-TRANS-GOLGI NETWORK 38 (RAT);Anti-trans-golgi network protein 2
CAS:
MF:
MW:0
EINECS:
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Mol File:Mol File
ANTI-TGN38 Structure
ANTI-TGN38 Chemical Properties
storage temp. -20°C
form buffered aqueous solution
Safety Information
MSDS Information
ANTI-TGN38 Usage And Synthesis
General DescriptionTrans-Golgi network integral membrane protein 2 (TGOLN2) is a heterodimeric type I integral membrane protein. It has a highly conserved N terminus which consists of a signal peptide. The C terminus comprises part of the lumenal domain, a membrane spanning region and cytoplasmic tail.
Biochem/physiol ActionsTrans-Golgi network integral membrane protein 2 (TGOLN2) cycles between the trans-Golgi network (TGN) and the cell surface via an early endosomal compartment. This movement is mediated by a tyrosine-based tetra peptide signal (SDYQRL) in the cytoplasmic domain. It plays an important role in the formation of exocytic vesicles at the TGN by functioning as a receptor for complexes of a cytoplasmic protein known as p62 and one GTP-binding protein. The cytoplasmic domain of TGOLN2 binds to the complex and is essential for budding to occur. Coupling of the segregation of secretory proteins to the budding of exocytic vesicles is mediated by it. The cytosolic domain of TGOLN2 interacts with AP2 clathrin adaptor complexes and also with the coiled coil region of a protein called neurabin.
ANTI-TGN38 Preparation Products And Raw materials
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