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Sigma-Aldrich
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021-61415566 800-8193336 |
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| Products Intro: |
Product Name:Anti-MITF antibody produced in rabbit
Purity:affinity isolated antibody Package:100UL Remarks:SAB2108175-100UL
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| | ANTI-MICROPHTHALMIA TRANSCRIPTION FACTOR Basic information |
| Product Name: | ANTI-MICROPHTHALMIA TRANSCRIPTION FACTOR | | Synonyms: | ANTI-MITF;ANTI-MICROPHTHALMIA TRANSCRIPTION FACTOR;Microphthalmia-associated transcription factor;MITF M1;Anti-Microphthalmia-associated transcription factor antibody produced in rabbit;Anti-MITF antibody produced in rabbit;Anti-WS2A | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-MICROPHTHALMIA TRANSCRIPTION FACTOR Structure]() |
| | ANTI-MICROPHTHALMIA TRANSCRIPTION FACTOR Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous glycerol solution |
| | ANTI-MICROPHTHALMIA TRANSCRIPTION FACTOR Usage And Synthesis |
| Uses | Anti-MITF antibody has been used in immunohistochemistry and chromatin immunoprecipitation. | | General Description | MITF (microphthalmia-associated transcription factor) is a basic helix-loop-helix, leucine-zipper transcription factor. It is located on human chromosome 3p13. | | Biochem/physiol Actions | MITF is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| | ANTI-MICROPHTHALMIA TRANSCRIPTION FACTOR Preparation Products And Raw materials |
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