6-羟基-2-氨甲基嘌呤
| 中文名称 | 6-羟基-2-氨甲基嘌呤 |
|---|---|
| 中文同义词 | 6-羟基-2-氨甲基嘌呤;2-甲氨基-6-羟基嘌呤;2-(甲基氨基)-1H-嘌呤-6(7H)-酮;6-羟基-2-氨甲基嘌呤 10G;2-(甲基氨基)-6,7-二氢-3H-嘌呤-6-酮;N2-甲基鸟嘌呤;2-(甲氨基)-3H-嘌呤-6(7H)-酮;化合物 N2-METHYLGUANINE |
| 英文名称 | 6-HYDROXY-2-METHYLAMINOPURINE |
| 英文同义词 | N2-METHYLGUANINE;6-HYDROXY-2-METHYLAMINOPURINE;2-(MethylaMino)-7H-purin-6-ol;2-(MethylaMino)-1H-purin-6(7H)-one;2-methylamino-3,7-dihydropurin-6-one;1,7-Dihydro-2-(methylamino)-6H-purin-6-one;6H-Purin-6-one,1,9-dihydro-2-(methylamino)-;2-(methylamino)-6,7-dihydro-3H-purin-6-one |
| CAS号 | 10030-78-1 |
| 分子式 | C6H7N5O |
| 分子量 | 165.15 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 10030-78-1.mol |
| 结构式 |  |
6-羟基-2-氨甲基嘌呤 性质
| 熔点 | >300 °C (decomp) |
|---|---|
| 密度 | 1.79±0.1 g/cm3(Predicted) |
| 储存条件 | 4°C, Inert atmosphere |
| 溶解度 | DMSO：< 1 mg/mL（不溶或微溶） |
| 形态 | 固体 |
| 酸度系数(pKa) | 9.86±0.20(Predicted) |
| 颜色 | 浅黄至卡其色 |
|
Human Endogenous Metabolite
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2-(Methylamino)-1H-purin-6(7H)-one (N2-methylguanine) is found within both helical and looped regions of RNA secondary structure, and it can exist in either the s-cis or the s-trans rotamer. If there is a rotational preference for the methyl group, the effect of 2-(Methylamino)-1H-purin-6(7H)-one substitution may be specific to the sequence context depending upon which face of the base participates in hydrogen bonding. 2-(Methylamino)-1H-purin-6(7H)-one (N2-methylguanine) is the principal kinetic barrier for reverse transcription in the 1340 bases proximal to the 5' end of E. coli 16S rRNA. Transcription intermediates correspond to attenuation at the positions of 2-(Methylamino)-1H-purin-6(7H)-one in the rRNA sequence. The relaxation time for elongation of the cDNA through m2G is approximately 3 min.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/08/19 | HY-101412 | 2-(Methylamino)-1H-purin-6(7H)-one | 1 mg | 520元 | |
| 2024/08/19 | HY-101412 | 6-羟基-2-氨甲基嘌呤 2-(Methylamino)-1H-purin-6(7H)-one | 10030-78-1 | 5mg | 1300元 |