| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Remarks:clone 22221, purified immunoglobulin, lyophilized powder
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| Company Name: |
R & D Systems
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| Tel: |
612 379 2956 |
| Email: |
info@rndsystems.com |
| Products Intro: |
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| | ANTI-HUMAN TNF RII EXTRACELLULAR DOMAIN Basic information |
| Product Name: | ANTI-HUMAN TNF RII EXTRACELLULAR DOMAIN | | Synonyms: | ANTI-TNF-RII, HUMAN;ANTI-TUMOR NECROSIS FACTOR SOLUBLE RECEPTOR TYPE II (TNF SRII), HUMAN;ANTI-TUMOR NECROSIS FACTOR SOLUBLE RECEPTOR II (TNF SRII), HUMAN;ANTI-HUMAN TNFRSF1B EXTRACELLULAR DOMAIN;ANTI-HUMAN TNF-RII;ANTI-HUMAN TNF-R II CD120B;ANTI-HUMAN TNF-R II, CD120B, CLONE MR2-1;ANTI-HUMAN TNF-R II, CD120B, CLONE MR2-1, MONOCLONAL ANTIBODY | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-HUMAN TNF RII EXTRACELLULAR DOMAIN Structure]() |
| | ANTI-HUMAN TNF RII EXTRACELLULAR DOMAIN Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder |
| | ANTI-HUMAN TNF RII EXTRACELLULAR DOMAIN Usage And Synthesis |
| Uses | Anti-Tumor Necrosis Factor Receptor II antibody may be used for immunocytochemistry at a working concentration of 8-25 μg/ml using human peripheral blood lymphocytes. The antibody is suitable for neutralization assays and protein microarray. The antibody was used for flow cytometry using human CD8 T cells. | | General Description | The tumor necrosis factor super family (TNFSF) consists of at least 19 transmembrane proteins with soluble forms that are generated by proteolysis. The biological effects of TNF are mediated by either type I or type II receptors. Type I receptors that are ubiquitously present on all cells whereas type II receptors are expressed only on cells of immune system (monocytes, macrophages, Langerhans cells) and endothelial cells. Receptors of TNFSF such as TNFR I and Fas have their own death domains that activate the apoptosis. Other receptors such as TNFR II do not have death domains and utilize TNF associated factors (TRAFs) to activate intracellular signaling. TNFR II activates NF-κB pathway via the activation of NIK. Monoclonal Anti-Tumor Necrosis Factor Receptor II antibody recognizes human TNFR II. |
| | ANTI-HUMAN TNF RII EXTRACELLULAR DOMAIN Preparation Products And Raw materials |
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