| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:FABP-IN-1
CAS:2132990-90-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:FABP-IN-1;FABP IN 1,FABPIN1
CAS:2132990-90-8
Purity:98% Package:10 mg;100 mg;25 mg;50 mg
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| | FABP-IN-1 Basic information |
| Product Name: | FABP-IN-1 | | Synonyms: | FABP-IN-1;FABP IN 1,FABPIN1;1,3-Cyclobutanedicarboxylic acid, 2,4-bis(2-methoxyphenyl)-, 1-(1-naphthalenyl) ester, (1β,2R,3α,4R)-rel- | | CAS: | 2132990-90-8 | | MF: | C30H26O6 | | MW: | 482.52 | | EINECS: | | | Product Categories: | | | Mol File: | 2132990-90-8.mol |  |
| | FABP-IN-1 Chemical Properties |
| Boiling point | 671.3±55.0 °C(Predicted) | | density | 1.280±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 200 mg/mL (414.49 mM; Need ultrasonic) | | pka | 4.10±0.70(Predicted) |
| | FABP-IN-1 Usage And Synthesis |
| Biological Activity | FABP-IN-1 (Compounds 4b) is a high affinity fatty acid binding protein (FABP) inhibitor. FABP-IN-1 inhibits FABP3, FABP5, and FABP7 with Ki values of 0.69 μM, 0.55 μM and 0.67 μM, respectively. FABP-IN-1 displays potent antinociceptive effects[1].
FABP-IN-1 (Compounds 4b; 20 mg/kg; intraperitoneal injection; for 90 minutes; male wild-type C57BL/6 mice) treatment displays potent antinociceptive effects in CFA model[1]. | | References | [1]. Yan S, et al. SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins. Eur J Med Chem. 2018 Jun 25;154:233-252. |
| | FABP-IN-1 Preparation Products And Raw materials |
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