| Company Name: |
Nanjing Shizhou Biology Technology Co.,Ltd
|
| Tel: |
025-85563444 18351873721 |
| Email: |
purchase@synzest.com |
| Products Intro: |
Product Name:2-Bromo-2,2-dimethyl-acetamido-PEG3-acid
CAS:2279944-67-9
Purity:95%HPLC Package:50mg;100mg;250mg;1g
|
| Company Name: |
Beijing Jin Ming Biotechnology Co., Ltd.
|
| Tel: |
010-60605840 15801484223; |
| Email: |
psaitong@jm-bio.com |
| Products Intro: |
Product Name:2-Bromo-2,2-dimethyl-acetamido-PEG3-acid
CAS:2279944-67-9
Purity:95% Package:100mg;250mg;1g
|
|
| | 2-Bromo-2,2-dimethyl-acetamido-PEG3-acid Basic information |
| | 2-Bromo-2,2-dimethyl-acetamido-PEG3-acid Chemical Properties |
| Boiling point | 526.3±50.0 °C(Predicted) | | density | 1.341±0.06 g/cm3(Predicted) | | pka | 4.28±0.10(Predicted) |
| | 2-Bromo-2,2-dimethyl-acetamido-PEG3-acid Usage And Synthesis |
| Biological Activity | 2-Bromo-22-dimethyl-acetamido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | 2-Bromo-2,2-dimethyl-acetamido-PEG3-acid Preparation Products And Raw materials |
|