化合物SY-640
中文名称 | 化合物SY-640 |
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中文同义词 | 化合物SY-640 |
英文名称 | Acetamide, N-(1,3-benzodioxol-5-ylmethyl)-N-methyl- |
英文同义词 | Acetamide, N-(1,3-benzodioxol-5-ylmethyl)-N-methyl-;Acetamide,inhibit,acnes,Propionibacterium,Endogenous Metabolite,hepatoprotective,Lipopolysaccharide,SY 640,SY640,Inhibitor,SY-640 |
CAS号 | 168705-70-2 |
分子式 | C11H13NO3 |
分子量 | 207.23 |
EINECS号 | |
相关类别 | |
Mol文件 | 168705-70-2.mol |
结构式 | ![]() |
化合物SY-640 性质
熔点 | 103 °C |
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沸点 | 349.2±21.0 °C(Predicted) |
密度 | 1.213±0.06 g/cm3(Predicted) |
储存条件 | Store at -20°C |
溶解度 | 二甲基亚砜:100 mg/mL(482.56 mM) |
酸度系数(pKa) | -0.58±0.70(Predicted) |
形态 | 液体 |
颜色 | 浅黄至黄色 |
Human Endogenous Metabolite
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SY-640 inhibits the number of liver-infiltrating cells and attenuates the increased expression of leukocyte function-associated antigen-1 on these cells.
SY-640 (Oral; 150 mg/kg; once daily for 7 days) significantly inhibits Propionibacterium acnes and Lipopolysaccharide-induced liver injury, but a single administration is without effect.
SY-640 (p.o.; 150 mg/kg; once daily for three days) significantly increases the liver microsomal cytochrome P-450 content and aminopyrine demethylase activity in mice. The hepatic microsomal aminopyrine demethylase activity is obviously inhibited two hours after oral administration of SY-640.