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| 3-Pyridinecarboxamide, 5-chloro-1,2-dihydro-6-hydroxy-2-oxo- Basic information |
| 3-Pyridinecarboxamide, 5-chloro-1,2-dihydro-6-hydroxy-2-oxo- Chemical Properties |
Melting point | 225-230 °C(Solv: ethanol (64-17-5)) | Boiling point | 381.9±42.0 °C(Predicted) | density | 1.70±0.1 g/cm3(Predicted) | pka | 4.50±1.00(Predicted) |
| 3-Pyridinecarboxamide, 5-chloro-1,2-dihydro-6-hydroxy-2-oxo- Usage And Synthesis |
Uses | 5-Chloro-6-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamide is a building block related to Favipiravir(F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever. |
| 3-Pyridinecarboxamide, 5-chloro-1,2-dihydro-6-hydroxy-2-oxo- Preparation Products And Raw materials |
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