Company Name: |
Bide Pharmatech Ltd.
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Tel: |
400-1647117 13681763483 |
Email: |
product02@bidepharm.com |
Products Intro: |
Product Name:6-(2,5-Bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl)benzo[d]thiazol-2(3H)-one CAS:2034181-36-5 Purity:98% Package:1mg;5mg;10mg;25mg;50mg;100mg; Remarks:BD01467625
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Company Name: |
Qi Qi hang Biotechnology Co., Ltd.
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Tel: |
15870833005 |
Email: |
2232044025@qq.com |
Products Intro: |
Product Name:AMPAreceptormodulator-2 CAS:2034181-36-5 Purity:99 Package:1kg Remarks:DZ0105
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2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]- manufacturers
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| 2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]- Basic information |
Product Name: | 2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]- | Synonyms: | 2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]-;AMPA receptor modulator-2;AMPA,AMPA receptor modulator-2,TARPγ,Ionotropic glutamate receptors,inhibit,Inhibitor,AMPA receptor modulator2,AMPA receptor modulator 2,iGluR;6-(2,5-Bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl)benzo[d]thiazol-2(3H)-one;6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]-2,3-dihydro-1,3-benzothiazol-2-one | CAS: | 2034181-36-5 | MF: | C15H6F6N4OS | MW: | 404.29 | EINECS: | | Product Categories: | | Mol File: | 2034181-36-5.mol | |
| 2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]- Chemical Properties |
density | 1.79±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMSO : 250 mg/mL (618.37 mM; Need ultrasonic)| | pka | 9.56±0.20(Predicted) | form | Solid | color | White to off-white | Water Solubility | Water : < 0.1 mg/mL (insoluble) |
| 2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]- Usage And Synthesis |
Biological Activity | AMPA receptor modulator-2 (Example 134) is a AMPA receptor modulator, with a pIC50 of 10.1 for TARPγ2 dependent AMPA receptor[1]. pIC50 = -lgIC50. | References | [1]. BERRY CYNTHIA G B (US), et al. AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS. Patent. WO2016176460. |
| 2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]- Preparation Products And Raw materials |
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