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BOC Sciences
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Product Name:Emeguisin A CAS:117032-54-9 Purity:>95% by HPLC Remarks:Emeguisin A is isolated from the fungus Emericella unguis. Emeguisin A exhibits potent antibacterial
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ChemeGen 中国
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Product Name:Emeguisin A CAS:117032-54-9 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Shanghai Yifei Biotechnology Co. , Ltd.
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Product Name:Emeguisin A CAS:117032-54-9 Purity:95% Package:100μg;500μg
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TargetMol Chemicals Inc.
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Product Name:Emeguisin A CAS:117032-54-9 Purity:详情请点击官网 Package:1 mg
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Cayman Chemical Company
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Product Name:Emeguisin A CAS:117032-54-9
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| 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 7-chloro-3,8-dihydroxy-4,9-dimethyl-1,6-bis(1-methyl-1-propenyl)- (9CI) Basic information |
Product Name: | 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 7-chloro-3,8-dihydroxy-4,9-dimethyl-1,6-bis(1-methyl-1-propenyl)- (9CI) | Synonyms: | 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 7-chloro-3,8-dihydroxy-4,9-dimethyl-1,6-bis(1-methyl-1-propenyl)- (9CI);Emeguisin A | CAS: | 117032-54-9 | MF: | C23H23ClO5 | MW: | 414.88 | EINECS: | | Product Categories: | | Mol File: | 117032-54-9.mol | ![11H-Dibenzo[b,e][1,4]dioxepin-11-one, 7-chloro-3,8-dihydroxy-4,9-dimethyl-1,6-bis(1-methyl-1-propenyl)- (9CI) Structure](CAS/20210305/GIF/117032-54-9.gif) |
| 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 7-chloro-3,8-dihydroxy-4,9-dimethyl-1,6-bis(1-methyl-1-propenyl)- (9CI) Chemical Properties |
Boiling point | 611.2±55.0 °C(Predicted) | density | 1.274±0.06 g/cm3(Predicted) | storage temp. | -20°C | solubility | DMSO: soluble; Methanol: soluble | form | A solid | pka | 7?+-.0.20(Predicted) |
| 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 7-chloro-3,8-dihydroxy-4,9-dimethyl-1,6-bis(1-methyl-1-propenyl)- (9CI) Usage And Synthesis |
Biological Activity | Emeguisin A is a depsidone fungal metabolite originally isolated from E. unguis.1 It is active against the bacteria S. aureus and methicillin-resistant S. aureus (MRSA; MIC = 0.5 μg/ml for both), the fungus C. neoformans (MIC = 0.5 μg/ml), and the protozoan P. falciparum (IC50 = 2.2 μM).2 | References | 1.Kawahara, N., Nozawa, K., Nakajima, S., et al.Isolation and structures of novel fungal depsidones, emeguisins A, B, and C, from Emericella unguisJ. Chem. Soc., Perkin Trans. 12611-2614(1988)
2.Klaiklay, S., Rukachaisirikul, V., Aungphao, W., et al.Depsidone and phthalide derivatives from the soil-derived fungus Aspergillus unguis PSU-RSPG199Tetrahedron Lett.57(39)4348-4351(2016) |
| 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 7-chloro-3,8-dihydroxy-4,9-dimethyl-1,6-bis(1-methyl-1-propenyl)- (9CI) Preparation Products And Raw materials |
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