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BOC Sciences
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1-631-485-4226; 16314854226 |
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Product Name:Preterramide C CAS:81469-77-4 Purity:>95% by HPLC Remarks:0
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767 |
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Product Name:Preterramide C CAS:81469-77-4 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Beijing Biocreative Technology Co., Ltd.
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15522676233 |
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3007606172@qq.com |
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Product Name:Preterramide C CAS:81469-77-4 Purity:99% HPLC Package:1.0mg; 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 2.0g; 5.0g;
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Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627 |
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customer_service@efebio.com |
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Product Name:Preterramide C CAS:81469-77-4 Purity:95% Package:250μg;1mg
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| Benzoic acid, 3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-, methyl ester Basic information |
Product Name: | Benzoic acid, 3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-, methyl ester | Synonyms: | Benzoic acid, 3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-, methyl ester;Preterramide C;3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-benzoic acid, methyl ester | CAS: | 81469-77-4 | MF: | C24H23N3O7 | MW: | 465.46 | EINECS: | | Product Categories: | | Mol File: | 81469-77-4.mol | |
| Benzoic acid, 3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-, methyl ester Chemical Properties |
Boiling point | 532.2±50.0 °C(Predicted) | density | 1.328±0.06 g/cm3(Predicted) | storage temp. | -20°C | form | A solid | pka | 10.73±0.70(Predicted) |
| Benzoic acid, 3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-, methyl ester Usage And Synthesis |
Biological Activity | Preterramide C is a fungal metabolite that has been found in A. terreus.1 It is active against S. aureus (MIC = 52.4 μM) but not E. aerogenes, P. aeruginosa, or C. albicans (MICs = >100 μM for all).2 Preterramide C inhibits the growth of L5178Y mouse lymphoma cells with an IC50 value of 0.1 μg/ml.3 It also inhibits nitric oxide (NO) production induced by LPS in RAW 264.7 cells (IC50 = 5.48 μM). | References | 1.He, F., Bao, J., Zhang, X.-Y., et al.Asperterrestide A, a cytotoxic cyclic tetrapeptide from the marine-derived fungus Aspergillus terreus SCSGAF0162J. Nat. Prod.76(6)1182-1186(2013)
2.Wang, Y., Zheng, J., Liu, P., et al.Three new compounds from Aspergillus terreus PT06-2 grown in a high salt mediumMar. Drugs9(8)1368-1378(2011)
3.Zhou, Y., Mandi, A., Debbab, A., et al.New austalides from the sponge-associated fungus Aspergillus sp.Eur. J. Org. Chem.306009-6019(2011) |
| Benzoic acid, 3,4,5-trimethoxy-2-[[2-[(3-pyridinylcarbonyl)amino]benzoyl]amino]-, methyl ester Preparation Products And Raw materials |
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