| Company Name: |
Chengdu Youngshe Chemical Co., Ltd.
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| Tel: |
+86-17380623303 +86-17380623303 |
| Email: |
Caroline@youngshechem.com |
| Products Intro: |
Product Name:LAH4
CAS:184776-51-0
Purity:95% Package:1G; 10G; 100G
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| Company Name: |
Hangzhou Peptidego Biotech Co.,Ltd.
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| Tel: |
0571-87213919 |
| Email: |
eric@peptidego.com |
| Products Intro: |
Product Name:LAH4
CAS:184776-51-0
Purity:95% or 98% HPLC Package:1mg；5mg；10mg；50mg；100mg,1g or according to customer's detail requirement.
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| | L-Alanine, L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-histidyl-L-histidyl-L-leucyl-L-alanyl-L-histidyl-L-leucyl-L-alanyl-L-leucyl-L-histidyl-L-leucyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-lysyl-L-lysyl- Basic information |
| | L-Alanine, L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-histidyl-L-histidyl-L-leucyl-L-alanyl-L-histidyl-L-leucyl-L-alanyl-L-leucyl-L-histidyl-L-leucyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-lysyl-L-lysyl- Chemical Properties |
| Boiling point | 2489.3±65.0 °C(Predicted) | | density | 1.201±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | L-Alanine, L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-histidyl-L-histidyl-L-leucyl-L-alanyl-L-histidyl-L-leucyl-L-alanyl-L-leucyl-L-histidyl-L-leucyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-lysyl-L-lysyl- Usage And Synthesis |
| Description | LAH4 is an antimicrobial peptide that strongly interacts with phospholipid membranes, exhibiting in vitro transfection efficiency. LAH4 exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities[1]. LAH4 mediates the transport of functional β-galactosidase, a large tetrameric protein of about 0.5 MDa, into the cell interior[2]. At acidic pH, LAH4 has exhibited a high tendency to interact strongly with and be adsorbed on anionic membrane[3]. | | References | [1]. Perrone B, et al. Lipid interactions of LAH4, a peptide with antimicrobial and nucleic acid transfection activities. Eur Biophys J. 2014 Nov;43(10-11):499-507. [2]. Moulay G, et al. Histidine-rich designer peptides of the LAH4 family promote cell delivery of a multitude of cargo. J Pept Sci. 2017 Apr;23(4):320-328. [3]. Islami M, et al. Study of orientation and penetration of LAH4 into lipid bilayer membranes: pH and composition dependence. Chem Biol Drug Des. 2014 Aug;84(2):242-52. |
| | L-Alanine, L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-histidyl-L-histidyl-L-leucyl-L-alanyl-L-histidyl-L-leucyl-L-alanyl-L-leucyl-L-histidyl-L-leucyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-lysyl-L-lysyl- Preparation Products And Raw materials |
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