120876-23-5

120876-23-5

中文名称120876-23-5
中文同义词醋酸普罗瑞林?, >99%
英文名称Protirelin acetate
英文同义词Protirelin acetate;Protirelin Acetate,TRF Acetate,TRH Acetate,TSH-RF Acetate, >99%;TRF Acetate;TRH Acetate;TSH-RF Acetate
CAS号120876-23-5
分子式C38H56N12O14
分子量904.92324
EINECS号
相关类别
Mol文件120876-23-5.mol
结构式120876-23-5 结构式

120876-23-5 性质

储存条件Store at -20°C
形态固体
颜色白色至米白色
水溶解性Water : 50 mg/mL (110.51 mM)

120876-23-5 用途与合成方法

Protirelin Acetate 是一种高度保守的神经肽,发挥促甲状腺激素 (TSH) 水平的激素控制作用,及神经调节功能。

Thyroid hormone receptor

Protirelin (TRH) is an evolutionarily ancient neuropeptide, having its origin before the divergence of protostomes and deuterostomes, and may ancestrally have been involved in the control of postembryonic growth and reproduction. The effect of the thyrotropin-releasing hormone (Protirelin, TRH), one of the hypothalamic releasing hormones, on body temperature is investigated in the rat. Protirelin, in doses of 1, 5, 10 and 20 mg/kg, is injected intraperitoneally to male Wistar rats weighing 200-250 g. Protirelin causes a temporary rise in body temperature dose-dependently. The thyroidectomized rats injected 20 mg/kg of Protirelin which induces a significant hyperthermia in the sham-operated animals, fail to show a rise in body temperature. The present results suggest that a release of thyroid hormone might participate in the hyperthermic action of Protirelin.

安全信息

MSDS信息

更新日期产品编号产品名称CAS号包装价格
2024/04/30HY-P0002AProtirelin acetate5 mg420元
2024/04/30HY-P0002A120876-23-5
Protirelin acetate
120876-23-510mM * 1mLin Water462元

120876-23-5 上下游产品信息

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