120876-23-5
中文名称 | 120876-23-5 |
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中文同义词 | 醋酸普罗瑞林?, >99% |
英文名称 | Protirelin acetate |
英文同义词 | Protirelin acetate;Protirelin Acetate,TRF Acetate,TRH Acetate,TSH-RF Acetate, >99%;TRF Acetate;TRH Acetate;TSH-RF Acetate |
CAS号 | 120876-23-5 |
分子式 | C38H56N12O14 |
分子量 | 904.92324 |
EINECS号 | |
相关类别 | |
Mol文件 | 120876-23-5.mol |
结构式 | ![]() |
120876-23-5 性质
储存条件 | Store at -20°C |
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形态 | 固体 |
颜色 | 白色至米白色 |
水溶解性 | Water : 50 mg/mL (110.51 mM) |
Thyroid hormone receptor
Protirelin (TRH) is an evolutionarily ancient neuropeptide, having its origin before the divergence of protostomes and deuterostomes, and may ancestrally have been involved in the control of postembryonic growth and reproduction. The effect of the thyrotropin-releasing hormone (Protirelin, TRH), one of the hypothalamic releasing hormones, on body temperature is investigated in the rat. Protirelin, in doses of 1, 5, 10 and 20 mg/kg, is injected intraperitoneally to male Wistar rats weighing 200-250 g. Protirelin causes a temporary rise in body temperature dose-dependently. The thyroidectomized rats injected 20 mg/kg of Protirelin which induces a significant hyperthermia in the sham-operated animals, fail to show a rise in body temperature. The present results suggest that a release of thyroid hormone might participate in the hyperthermic action of Protirelin.
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/04/30 | HY-P0002A | Protirelin acetate | 5 mg | 420元 | |
2024/04/30 | HY-P0002A | 120876-23-5 Protirelin acetate | 120876-23-5 | 10mM * 1mLin Water | 462元 |