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Product Name:Isonanangenine B
CAS:1623153-14-9
Purity:>95% by HPLC Remarks:Isonanangenine B is a drimane sesquiterpene lactone isolated from Aspergillus nanangensis. Ionanpuri
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ChemeGen 中国
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18818260767 |
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Product Name:Isonanangenine B
CAS:1623153-14-9
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627 |
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Product Name:Isonanangenine B
CAS:1623153-14-9
Purity:95% Package:1mg;5mg
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TargetMol Chemicals Inc.
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15002134094 |
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Product Name:Isonanangenine B
CAS:1623153-14-9
Purity:详情请点击官网 Package:1 mg
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| | Isonanangenine B Basic information |
| Product Name: | Isonanangenine B | | Synonyms: | Isonanangenine B;Hexanoic acid, (5R,5aS,9R,9aR,9bS)-1,3,5,5a,6,7,8,9,9a,9b-decahydro-9,9b-dihydroxy-6,6,9a-trimethyl-3-oxonaphtho[1,2-c]furan-5-yl ester;(5R,5aS,9R,9aR,9bS)-1,3,5,5a,6,7,8,9,9a,9b-decahydro-9,9b-dihydroxy-6,6,9a-trimethyl-3-oxonaphtho[1,2-c]furan-5-yl ester, hexanoic acid | | CAS: | 1623153-14-9 | | MF: | C21H32O6 | | MW: | 380.48 | | EINECS: | | | Product Categories: | | | Mol File: | 1623153-14-9.mol |  |
| | Isonanangenine B Chemical Properties |
| Boiling point | 541.9±50.0 °C(Predicted) | | density | 1.21±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | form | A solid | | pka | 11.46±0.70(Predicted) |
| | Isonanangenine B Usage And Synthesis |
| Biological Activity | Isonanangenine B is a drimane sesquiterpene lactone that has been found in Aspergillus.1,2 It decreases survivin mRNA expression in a reporter assay when used at concentrations of 13.6, 18.42, and 26.31 μM. Isonanagenine B (18.42 μM) inhibits STAT3 and NF-κB binding to the survivin promoter in chromatin immunoprecipitation (ChIP) assays. It also induces apoptosis in COLO 320DM cells. | | References | 1.Lacey, H.J., Gilchrist, C.L.M., Crombie, A., et al.Nanangenines: Drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensisBeilstein J. Org. Chem.152631-2643(2019)
2.Felix, S., Sandjo, L.P., Opatz, T., et al.SF002-96-1, a new drimane sesquiterpene lactone from an Aspergillus species, inhibits survivin expressionBeilstein J. Org. Chem.92866-2876(2013) |
| | Isonanangenine B Preparation Products And Raw materials |
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