Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]- manufacturers
- HG106
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- $58.00 / 1mg
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2024-11-05
- CAS:928712-10-1
- Min. Order:
- Purity: 99.62%
- Supply Ability: 10g
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| Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]- Basic information |
| Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]- Chemical Properties |
density | 1.40±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMSO: 21 mg/mL (66.30 mM);Ethanol: Insoluble | pka | 10.89±0.43(Predicted) | form | Solid | color | Off-white to light yellow | Water Solubility | Water: Insoluble |
| Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]- Usage And Synthesis |
Biological Activity | HG106, a potent SLC7A11 inhibitor, leads to enhanced ROS generation, ER stress, and ultimately growth arrest specifically in KRAS-mutant lung adenocarcinoma (LUAD). | References | [1] Hu K, et al. J Clin Invest. 2020 Apr 1;130(4):1752-1766. |
| Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]- Preparation Products And Raw materials |
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