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Propanoic acid, 2,2-dimethyl-, 1,1′,1′′,1′′′-[[2-(2-thiazolylamino)ethylidene]bis[phosphinylidynebis(oxymethylene)]] ester

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Propanoic acid, 2,2-dimethyl-, 1,1′,1′′,1′′′-[[2-(2-thiazolylamino)ethylidene]bis[phosphinylidynebis(oxymethylene)]] ester Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Products Intro: Product Name:HUN47990
CAS:1950647-99-0
Package:100mg;2500USD|25mg;1520USD|50mg;1980USD
Company Name: Jiangsu yize medical technology co. LTD  
Tel: 18962082606
Email: 3394205705@qq.com
Products Intro: Product Name:Propanoic acid, 2,2-dimethyl-, 1,1′,1′′,1′′′-[[2-(2-thiazolylamino)ethylidene]bis[phosphinylidynebis(oxymethylene)]] ester
CAS:1950647-99-0
Purity:95% Package:1g/;5g/
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:HUN47990
CAS:1950647-99-0
Package:100mg/RMB 17500;25mg/RMB 10600;50mg/RMB 13800

Propanoic acid, 2,2-dimethyl-, 1,1′,1′′,1′′′-[[2-(2-thiazolylamino)ethylidene]bis[phosphinylidynebis(oxymethylene)]] ester manufacturers

  • HUN47990
  • HUN47990 pictures
  • $2500.00 / 100mg
  • 2024-10-28
  • CAS:1950647-99-0
  • Min. Order:
  • Purity:
  • Supply Ability: 10g
Propanoic acid, 2,2-dimethyl-, 1,1′,1′′,1′′′-[[2-(2-thiazolylamino)ethylidene]bis[phosphinylidynebis(oxymethylene)]] ester Basic information
Product Name:Propanoic acid, 2,2-dimethyl-, 1,1′,1′′,1′′′-[[2-(2-thiazolylamino)ethylidene]bis[phosphinylidynebis(oxymethylene)]] ester
Synonyms:Propanoic acid, 2,2-dimethyl-, 1,1′,1′′,1′′′-[[2-(2-thiazolylamino)ethylidene]bis[phosphinylidynebis(oxymethylene)]] ester;HUN47990
CAS:1950647-99-0
MF:C29H50N2O14P2S
MW:744.73
EINECS:
Product Categories:
Mol File:1950647-99-0.mol
Propanoic acid, 2,2-dimethyl-, 1,1′,1′′,1′′′-[[2-(2-thiazolylamino)ethylidene]bis[phosphinylidynebis(oxymethylene)]] ester Structure
Propanoic acid, 2,2-dimethyl-, 1,1′,1′′,1′′′-[[2-(2-thiazolylamino)ethylidene]bis[phosphinylidynebis(oxymethylene)]] ester Chemical Properties
Boiling point 738.5±70.0 °C(Predicted)
density 1.256±0.06 g/cm3(Predicted)
pka4.07±0.10(Predicted)
Safety Information
MSDS Information
Propanoic acid, 2,2-dimethyl-, 1,1′,1′′,1′′′-[[2-(2-thiazolylamino)ethylidene]bis[phosphinylidynebis(oxymethylene)]] ester Usage And Synthesis
DescriptionHUN47990 is a bisphosphonate (BP) prodrug with antitumor activity. HUN47990 potently inhibits the in vitro growth of a variety of tumor cell lines, especially hematopoietic cell lines, at nanomolar concentrations. HUN47990 inhibited the prenylation of the RAP1A small GTPase signaling protein at concentrations as low as 1-10 nM. HUN47990 slowed the growth of human bladder cancer cells in an immunodeficient mouse model. HUN47990 is significantly more active than zoledronic acid, the most active FDA-approved BP, and a potential anti-cancer therapeutic. HUN47990 was first reported in ChemMedChem. 2016 Dec 16;11(24):2656-2663 (compound 7). This product has no formal name at the moment.
Propanoic acid, 2,2-dimethyl-, 1,1′,1′′,1′′′-[[2-(2-thiazolylamino)ethylidene]bis[phosphinylidynebis(oxymethylene)]] ester Preparation Products And Raw materials
Tag:Propanoic acid, 2,2-dimethyl-, 1,1′,1′′,1′′′-[[2-(2-thiazolylamino)ethylidene]bis[phosphinylidynebis(oxymethylene)]] ester(1950647-99-0) Related Product Information
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