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YM-49598

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YM-49598 Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354
Email: support@targetmol.com
Products Intro: Product Name:YM49598；YM 49598;YM-49598
CAS:738575-62-7
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Email: marketing@tsbiochem.com
Products Intro: Product Name:YM49598;YM49598
CAS:738575-62-7
Purity:98% Package:5 mg
YM-49598 Basic information
Product Name:YM-49598
Synonyms:YM 49598;YM49598;YM-49598
CAS:738575-62-7
MF:C36H45Cl2N2O2+
MW:608.67
EINECS:
Product Categories:
Mol File:738575-62-7.mol
YM-49598 Structure
YM-49598 Chemical Properties
Safety Information
MSDS Information
YM-49598 Usage And Synthesis
DescriptionYM49598 is a novel non-peptide tachykinin receptor antagonist. YM49598 exhibited high binding affinities at NK(2) (pK(i) = 9.94 +/- 0.03) and NK(1) (pK(i) = 9.09 +/- 0.02) receptors, respectively. YM-49598 was almost inactive but produced a potent inhibition (IC(50) = 11 +/- 7 microg x kg(-1)) of the contraction of the rat urinary bladder induced by challenge with the NK(1)-selective receptor agonist [Sar9,Met(O(2))11]substance P sulphone (0.3 microg x kg(-1)).
YM-49598 Preparation Products And Raw materials
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