| Company Name: |
Shanghai Kewel Chemical Co., Ltd.
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| Tel: |
021-64609169 18901607656 |
| Email: |
greensnown@163.com |
| Products Intro: |
Product Name:Cetirizine Impurity 11 DiHydrochloride（Cetirizine EP Impurity C DiHydrochloride）
CAS:2702511-37-1
Purity:95+ HPLC; Package:10mg;25mg;50mg;100mg
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| Company Name: |
Hubei Yangxin Medical Technology Co., Ltd.
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| Tel: |
15374522761 |
| Email: |
3003392093@qq.com |
| Products Intro: |
Product Name:Cetirizine EP Impurity C
CAS:2702511-37-1
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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| Company Name: |
Hefei fuya biotechnology co. LTD
|
| Tel: |
18096409024 |
| Email: |
sales02@foreversyn.com |
| Products Intro: |
Product Name:Cetirizine EP Impurity C DiHCl Salt
CAS:2702511-37-1
Purity:95% HPLC Package:100MG;500MG
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| | Acetic acid, 2-[2-[4-[(2-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride (1:2) Basic information |
| | Acetic acid, 2-[2-[4-[(2-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride (1:2) Chemical Properties |
| storage temp. | -20°C, away from moisture | | solubility | DMSO : 100 mg/mL (216.54 mM; Need ultrasonic)| | | form | Solid | | color | White to Off-White | | Water Solubility | Water : 83.33 mg/mL (180.44 mM; Need ultrasonic) | | Stability: | Hygroscopic |
| | Acetic acid, 2-[2-[4-[(2-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride (1:2) Usage And Synthesis |
| Uses | Cetirizine (C281100) impurity as histamine inhibitor agent. | | Biological Activity | Cetirizine Impurity C dihydrochloride is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist[1][2]. | | References | [1]. Shih MY, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29(5):480-5. [2]. Shimizu T, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34(1):103-9. |
| | Acetic acid, 2-[2-[4-[(2-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride (1:2) Preparation Products And Raw materials |
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