| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:NSC43067 >=98% (HPLC)
CAS:26903-26-4
Purity:98% (HPLC) Package:25mg;5mg Remarks:NULL
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| Company Name: |
Riedel-de Haen AG
|
| Tel: |
800 558-9160 |
| Email: |
|
| Products Intro: |
Product Name:NSC43067
CAS:26903-26-4
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| | AIDS124653 Basic information |
| Product Name: | AIDS124653 | | Synonyms: | AIDS124653;1-(5-Methyl-2-thienyl)-3-phenyl-2-Propen-1-one;1-(5-Methyl-thiophen-2-yl)-3-phenyl-propenone;NSC 43067;NSC43067;NSC43067 >=98% (HPLC);2-Propen-1-one, 1-(5-methyl-2-thienyl)-3-phenyl- | | CAS: | 26903-26-4 | | MF: | C14H12OS | | MW: | 228.31 | | EINECS: | | | Product Categories: | | | Mol File: | 26903-26-4.mol |  |
| | AIDS124653 Chemical Properties |
| Boiling point | 379.8±42.0 °C(Predicted) | | density | 1.167±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: >20mg/mL | | form | powder | | color | light yellow to light tan |
| | AIDS124653 Usage And Synthesis |
| Biochem/physiol Actions | NSC43067 is a Cyclin-dependent kinase (Cdk) inhibitor which binds to a novel conserved site on Cdk, presumably the p27 binding pocket. The binding apparently directly induces Cdk1, Cdk2, and Cdk4 protein aggregation. Cdks 1, 2, 4, and 6 are the key Cdks that regulate the cell cycle, and are a target for a cancer treatment. NSC43067 arrests the cell cycle at the G0/G1 phase at lower concentrations and at the G2/M cell cycle phase at higher concentrations. The action appears to be reversible. |
| | AIDS124653 Preparation Products And Raw materials |
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